ArticleAnimals : an open access journal from MDPI2026
Genomic Signatures of Selection Reveal Breed-Specific and Shared Adaptive Regions in South African Beef Cattle.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In genetics and evolutionary biology, selection signatures refer to distinct genomic patterns that reflect the action of natural and artificial selection on populations over time. Detecting such signatures provides critical insights into adaptive evolution and breed differentiation, especially in livestock populations subjected to diverse production environments and breeding objectives. In this study, a total of 96 samples were collected from four different cattle breeds, namely, South African indigenous Nguni (n = 28), Bonsmara (n = 21), Angus (n = 22), and Simmental (n = 25). The samples were genotyped using the Illumina Bovine SNP 150K BeadChip and subjected to quality control. Selection signatures were identified using the integrated haplotype score (iHS) method and the fixation index (Fst) method to assess the genetic differences between breeds. The complementary application of within-population and cross-population approaches enabled the detection of both recent and divergent selective pressures. A total of twelve regions were found to be under selection, with
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