Evidence map›Paper›PMID 42277917›Full record

ArticleImplementation science communications2026

Outcomes of a penicillin allergy de-labelling implementation intervention in a UK hospital: a prospective, single centre, type 2 hybrid effectiveness-implementation study evaluated using mixed methods.

Neil Powell, Daniel Hearsey, Robert West, Mathew Upton, Bridie Kent, Sarah Tonkin-Crine, Jonathan Sandoe

Abstract read
In one paragraph

Article in Implementation science communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neil PowellPharmacy Department Royal Cornwall Hospital Trust, Truro, Cornwall, UK. neil.powell2@nhs.net.
Daniel HearseyPharmacy Department Royal Cornwall Hospital Trust, Truro, Cornwall, UK.
Robert WestLeeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Mathew UptonSchool of Biomedical Sciences, University of Plymouth, Plymouth, UK.
Bridie KentSchool of Nursing and Midwifery, University of Plymouth, Plymouth, UK.
Sarah Tonkin-CrineNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Jonathan SandoeLeeds Institute of Medical Research, University of Leeds, Leeds, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-allergy specialist healthcare workers removing low-risk penicillin allergy (penA) records, enabling patients to receive penicillin antibiotics, is safe but not common practice. We developed a behavioural change implementation intervention to support non-allergist healthcare workers to remove incorrect penA records from adult inpatients (penicillin allergy de-labelling; PADL). This study aimed to evaluate the effectiveness of the implementation intervention strategy and its impact on delabelling and antibiotic prescribing.

methodsThe implementation intervention was launched 10

resultsBetween 10

conclusionsThe PADL implementation intervention successfully increased non-specialist workforce PADL of low-risk patients. There is opportunity to further optimise PADL but competing priorities are a challenge. We found non-statistically significant impact of PADL on antibiotic use.

Identifiers

PMID42277917
PMCPMC13488184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.