Evidence map›Paper›PMID 42277840›Full record

ArticleJournal of neuroengineering and rehabilitation2026

Biomechanical effects of passive exosuit assistance on tibiofemoral loading and dynamic stability during downhill walking.

Alireza Nasirzadeh, WooIhl Kim, Jaeha Yang, Harry G Driscoll, Giuk Lee

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Article in Journal of neuroengineering and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Alireza NasirzadehSchool of Mechanical Engineering, Chung-Ang University, Seoul, South Korea.
WooIhl KimDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, USA.
Jaeha YangSchool of Mechanical Engineering, Chung-Ang University, Seoul, South Korea.
Harry G DriscollSchool of Mechanical Engineering, Chung-Ang University, Seoul, South Korea.
Giuk LeeSchool of Mechanical Engineering, Chung-Ang University, Seoul, South Korea. giuklee@cau.ac.kr.

Funding

Industrial Strategic Technology Development Program supported by the Ministry of Trade, Industry, & Energy (MOTIE, Korea) No. 20007058National Research Foundation of Korea (NRF) grant provided by the Korean government (MSIT) No. RS-2025-00555545
6 · The paper itself

Abstract

backgroundDownhill walking demands significant eccentric muscle activity at the knee, which increases tibiofemoral joint contact force (TFCF) and challenges gait stability. However, it remains unclear whether passive exosuits can reduce TFCF during downhill walking without compromising dynamic stability. This study investigated the biomechanical effectiveness of a passive trunk-to-thigh soft exosuit in decreasing TFCF and examining its effects on dynamic stability during downhill walking.

methodsFourteen healthy male participants walked on an instrumented treadmill set at a - 15° decline at 1.0 m·s⁻¹ under both unassisted and assisted conditions. Knee joint kinetics, TFCF, and dynamic stability parameters were estimated using a subject-specific full-body musculoskeletal model. Statistical Parametric Mapping (SPM) and paired t-tests were used to analyze continuous waveforms and discrete metrics, respectively.

resultsThe exosuit decreased biological stance phase TFCF impulse by ~7% (axial) and ~6% (resultant). Notably, participants adopted shorter, higher-cadence, and wider steps with the exosuit, suggesting that the reduced loading was driven concurrently by both the device's direct support and user-driven gait adaptations. SPM identified a significant decrease in knee joint power generation during mid-stance (23-29% gait cycle (GC)). Additionally, the ML margin of stability (MoS) significantly increased by 7.4%, while the anteroposterior (AP) MoS remained unchanged.

conclusionsThese results indicate that the current passive assistance can reduce cumulative tibiofemoral loading during downhill walking. Concurrently, the increased lateral margin of stability reflects a more cautious, wide-based gait strategy. These outcomes demonstrate that the device reduced joint loading through an intertwined combination of direct mechanical resistance and the induction of a joint-protective, shorter-step gait strategy. Consequently, passive wearable devices represent a promising approach for joint load management during downhill walking.

Indexed as

WalkingAdultBiomechanical PhenomenaGaitHumansKnee JointMaleTibiofemoral JointYoung AdultDownhill walkingDynamic stabilityJoint contact forcePassive exosuitTibiofemoral loading

Identifiers

PMID42277840
PMCPMC13483756

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.