Evidence map›Paper›PMID 42277791›Full record

ArticleBMC women's health2026

Effect of different long-acting reversible contraceptive methods on female sexual function: a retrospective cohort study.

Sha Ye, Lin Ma, Yepei Huang, Bisha Su, Yining Cao, Jian Huang, Jun Zhu

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Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Sha YeDepartment of Obstetrics and Gynecology, CiXi Maternity and Child Health Care Hospital, Ningbo, Zhejiang, 315300, China.
Lin MaDepartment of Gynecology, Hangzhou Women's Hospital, Hangzhou, Zhejiang, 310008, China.
Yepei HuangDepartment of Ultrasound, Women's Hospital, School of Medicine Zhejiang University, Hangzhou, Zhejiang, 310006, China.
Bisha SuDepartment of the Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310000, China.
Yining CaoDepartment of the Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310000, China.
Jian Huang *Department of Gynecology, Hangzhou Women's Hospital, Hangzhou, Zhejiang, 310008, China. huangjian96e90@163.com.
Jun Zhu *Department of Gynecology, Hangzhou Women's Hospital, Hangzhou, Zhejiang, 310008, China. zj5978@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of long-acting reversible contraception (LARC) on female sexual function remains a controversial and often overlooked issue. This study aimed to evaluate the effects of three common LARC methods on female sexual function.

methodsThis retrospective cohort study included 90 women, divided into three groups based on their chosen contraceptive: copper-containing intrauterine device (Cu-IUD, n = 30), levonorgestrel intrauterine system (LNG-IUS, n = 30), and the etonogestrel subcutaneous implant (Implanon, n = 30). Changes in sexual frequency and partner sexual satisfaction were recorded. Sexual function was assessed using the Female Sexual Function Index (FSFI) prior to insertion and at one, three, and six months post-insertion. Female sexual dysfunction (FSD) was defined as an FSFI total score of ≤ 19. Differences in these outcomes were compared among the three groups and across the different time points.

resultsThe frequency of sexual activity at six months post-insertion was significantly higher than at one month (p < 0.001) and three months (p = 0.034). Cu-IUD users reported significantly better partner sexual satisfaction compared to LNG-IUS users (B=-2.267, p < 0.001) and Implanon users (B=-2.072, p < 0.001). LNG-IUS users had the lowest total FSFI scores at all assessed time points (p = 0.004), while Cu-IUD users scored highest in the desire and satisfaction domains (p < 0.001 and p = 0.003, respectively). Both Cu-IUD and Implanon users reported better outcomes in lubrication and orgasm compared to LNG-IUS users (p < 0.001 and p = 0.004, respectively). Implanon users scored highest in the pain domain (p = 0.002). No significant differences were observed in the arousal domain at six months. FSD was significantly associated with the type of LARC used, a history of abortion, and changes in the frequency of sexual activity. Specifically, LNG-IUS users had a higher probability of experiencing FSD than Implanon users (p = 0.023). A history of abortion (p = 0.005) and a decreased frequency of sexual activity (p < 0.001) were identified as independent risk factors for FSD.

conclusionsThis study reveals that the LNG-IUS was associated with the poorest sexual function outcomes and a higher risk of FSD. Given the differences observed across various dimensions, clinicians can provide more personalized counseling when recommending contraceptive options. Additionally, dynamic follow-up for women using LARC is crucial, particularly within the first three months after insertion.

Indexed as

Contraceptive Agents, FemaleDesogestrelIntrauterine Devices, CopperLong-Acting Reversible ContraceptionSexual BehaviorSexual Dysfunction, PhysiologicalAdultFemaleHumansLevonorgestrelRetrospective StudiesYoung AdultContraceptive Agents, FemaleDesogestreletonogestrelLevonorgestrelFemale sexual dysfunctionFemale sexual functionLong-acting reversible contraceptiveSexuality

Identifiers

PMID42277791
PMCPMC13483484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.