Evidence map›Paper›PMID 42277634›Full record

ArticleBMC genomics2026

TWGFD: an integrative platform for tetraploid wheat gene family analysis.

Qinglin Ke, Tingting Li, Yiting Su, Han Lin, You Xu, Mengxing Wang, Yihan Li, Xiaojun Nie, Licao Cui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Qinglin Ke *College of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China.
Tingting Li *College of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China.
Yiting SuCollege of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China.
Han LinCollege of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China.
You XuCollege of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China.
Mengxing WangCollege of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China.
Yihan LiCollege of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China. liyihan@jxau.edu.cn.
Xiaojun NieState Key Laboratory of Crop Stress Biology in Arid Areas, College of Agronomy, Northwest A&F University, Yangling, Shaanxi, 712100, China. small@nwsuaf.edu.cn.
Licao CuiCollege of Bioscience and Engineering, Jiangxi Agricultural University, Nanchang, Jiangxi, 330045, China. cuilicao@jxau.edu.cn.

Funding

National Natural Science Foundation of China 32360157National Natural Science Foundation of China U22A20457Natural Science Foundation of Jiangxi Province 20232BAB205012
6 · The paper itself

Abstract

Gene families, primarily are composed of transcription factors, comprise evolutionarily conserved orthologs derived from common ancestors, characterized by shared sequence homology, structural domains, and fundamental roles in biological processes including development, growth, and environmental adaptation. As the immediate progenitor of hexaploid bread wheat (Triticum aestivum), tetraploid wheat constitutes both a vital industrial crop and a critical genetic reservoir, harboring numerous agronomically important stress-resistance traits. Systematic characterization of its gene families is imperative for elucidating functional and evolutionary mechanisms, yet dedicated analytical resources remain unavailable. To address this gap, we developed the inaugural Tetraploid Wheat Gene Family Database (TWGFD; http://triticumgfdb.com ), integrating 92 gene families encompassing 11,781 wild emmer (T. dicoccoides) and 13,357 durum wheat (T. durum) genes. This multi-omics platform delivers eight analytical modules: gene annotations, structural architectures, cis-regulatory elements, conserved protein motifs, phylogenetic relationships, expression profiles, ortholog identification, and nucleotide variation analysis. TWGFD's interactive interface enables gene retrieval, BLAST alignment, and bulk data downloads. This resource accelerates research on wheat domestication, adaptive evolution, and agronomic trait discovery.

Indexed as

Databases, GeneticGenes, PlantMultigene FamilyTetraploidyTriticumComputational BiologyGenomicsMolecular Sequence AnnotationPhylogenyPlant ProteinsPlant ProteinsDatabaseGene familyMulti-omicsTetraploid wheat

Identifiers

PMID42277634
PMCPMC13495266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.