Evidence map›Paper›PMID 42277599›Full record

ReviewInternal medicine journal2026

Organ-sparing management of luminal gastrointestinal cancers: current and emerging approaches.

Cassidy M Van Stiphout, Abigail Miller, Mia Shepherdson, Tarik Sammour, Sina Vatandoust, Tim Price, Tim Bright, Dayan Defontgalland, Christos S Karapetis, Amitesh C Roy

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Internal medicine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cassidy M Van StiphoutCollege of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.ORCID https://orcid.org/0009-0004-5602-0470
Abigail MillerDepartment of Medical Oncology, Flinders Medical Centre, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0002-3043-7401
Mia ShepherdsonCollege of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0002-6004-4764
Tarik SammourDepartment of Surgery, Adelaide University, Adelaide, South Australia, Australia.
Sina VatandoustCollege of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0002-4815-0994
Tim PriceDepartment of Medical Oncology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.
Tim BrightDepartment of Oesophago-gastric Surgery, Flinders Medical Centre, Adelaide, Australia.ORCID https://orcid.org/0000-0003-3700-5262
Dayan DefontgallandDepartment of Oesophago-gastric Surgery, Flinders Medical Centre, Adelaide, Australia.
Christos S KarapetisCollege of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Amitesh C RoyCollege of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of luminal gastrointestinal malignancies with curative intent has traditionally required a combination of systemic treatments and complex surgical resections, which carry risks to function and quality of life. Organ-sparing approaches to treating gastrointestinal malignancies have advanced significantly. With increasing efficacy of upfront systemic and radiation therapies, select patients can safely avoid radical surgery while maintaining oncologic outcomes. This review discusses current and future organ-sparing approaches in the management of gastro-oesophageal, colon, rectal and anal cancers.

Indexed as

Gastrointestinal NeoplasmsOrgan Sparing TreatmentsCombined Modality TherapyHumansNeoadjuvant Therapycombined modality therapygastrointestinal neoplasmsneoadjuvant therapyorgan sparing treatmentsreview

Identifiers

PMID42277599
PMCPMC13288307

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.