Evidence map›Paper›PMID 42277364›Full record

ReviewCommunications biology2026

Chlamydia trachomatis orchestrates multifaceted host cell manipulation for immune evasion.

Deepthi Krishnan Nair Geetha, Paridhi Agarwal, Athulya Thiruvacholayil, Karthika Rajeeve

Abstract readReview
In one paragraph

Review in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deepthi Krishnan Nair GeethaInfection Biology Laboratory, Pathogen Biology Department, BRIC-Rajiv Gandhi Centre for Biotechnology, Poojappura, Thiruvananthapuram, Kerala, India.ORCID 0000-0003-2581-8098
Paridhi AgarwalInfection Biology Laboratory, Pathogen Biology Department, BRIC-Rajiv Gandhi Centre for Biotechnology, Poojappura, Thiruvananthapuram, Kerala, India.
Athulya ThiruvacholayilInfection Biology Laboratory, Pathogen Biology Department, BRIC-Rajiv Gandhi Centre for Biotechnology, Poojappura, Thiruvananthapuram, Kerala, India.
Karthika RajeeveInfection Biology Laboratory, Pathogen Biology Department, BRIC-Rajiv Gandhi Centre for Biotechnology, Poojappura, Thiruvananthapuram, Kerala, India. karaj@rgcb.res.in.ORCID 0009-0002-1246-0082

Funding

DST | Science and Engineering Research Board (SERB) SPF/2021/000051DST | Science and Engineering Research Board (SERB) SRG/2021/001207
6 · The paper itself

Abstract

Chlamydia trachomatis is an obligate intracellular sexually transmitted human pathogen and a major cause of ocular and urogenital infections worldwide, causing significant reproductive and neonatal complications. Despite eliciting host immune responses, C. trachomatis infections frequently remain asymptomatic, contributing to silent epidemic that often progress to chronic disease. This paradox reflects the remarkable ability of the pathogen to intricately manipulate host cell survival pathways and immune signalling networks. This review synthesizes current knowledge of C. trachomatis pathogenesis and host-pathogen interactions, with a particular emphasis on immune evasion strategies, the implications of which might be effective for therapeutic and preventive approaches.

Indexed as

Chlamydia InfectionsChlamydia trachomatisHost-Pathogen InteractionsImmune EvasionAnimalsHumansSignal Transduction

Identifiers

PMID42277364
PMCPMC13260453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.