Dose‑dependent association of smoking exposure with HDL subfraction cholesterol content.

Péter Pikó, Nóra Kovács, László Pál, Sándor Szücs, Ildikó Seres, György Paragh, Róza Ádány

Abstract read

In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Péter PikóDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 26. Kassai Street, Debrecen, 4028, Hungary. piko.peter@med.unideb.hu.

Nóra KovácsDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 26. Kassai Street, Debrecen, 4028, Hungary.

László PálDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 26. Kassai Street, Debrecen, 4028, Hungary.

Sándor SzücsDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 26. Kassai Street, Debrecen, 4028, Hungary.

Ildikó SeresDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 98. Nagyerdei Krt, Debrecen, 4032, Hungary.

György ParaghDepartment of Internal Medicine, Faculty of Medicine, University of Debrecen, 98. Nagyerdei Krt, Debrecen, 4032, Hungary.

Róza ÁdányDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 26. Kassai Street, Debrecen, 4028, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smoking has a significant effect on plasma lipid concentrations, especially high‑density lipoprotein (HDL)-associated cholesterol and its distribution across HDL subfractions, which are critical for cardiovascular health. The present study aimed to investigate the association between smoking and HDL‑cholesterol (HDL‑C) concentration, as well as the cholesterol distribution between different HDL subfractions, and other lipid parameters, including total cholesterol (TC), low‑density lipoprotein cholesterol (LDL‑C), triglycerides (TG), apolipoprotein AI (ApoAI), apolipoprotein B100 (ApoB100), and the TG/HDL‑C and ApoB100/ApoAI ratios, in a Hungarian cohort of 314 (137 nonsmokers and 177 smokers). HDL‑associated cholesterol was fractionated into ten electrophoretic subfractions (HDL‑1 to HDL‑10) and three subclasses (HDL‑L, HDL‑I, HDL‑S) using the Lipoprint

Indexed as

Cholesterol, HDLSmokingAdultAgedApolipoprotein A-IFemaleHumansMaleMiddle AgedTriglyceridesApolipoprotein A-ICholesterol, HDLTriglyceridesHDL-associated cholesterol distributionHDL subfraction cholesterol contentHigh-density lipoprotein cholesterolLipid profile alterationsRegression analysisSmoking exposure

Identifiers

PMID42277343

DOI10.1038/s41598-026-57573-4

PMCPMC13434783

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