Evidence map›Paper›PMID 42277290›Full record

ArticleNature aging2026

An open competition for biomarkers of aging.

Kejun Ying, Seth Paulson, Julian Reinhard, Jakob Träuble, Stefan Jokiel, Raphael Lermer, Lucas Paulo de Lima Camillo, Korbinian Traeuble, Biomarkers of Aging Consortium, Dane Gobel and 7 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Kejun YingDivision of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. keying@stanford.edu.ORCID http://orcid.org/0000-0002-1791-6176
Seth PaulsonMethuselah Foundation, Washington, DC, USA.
Julian ReinhardGlobal Bioinformatics, Evotec SE, Hamburg, Germany.ORCID http://orcid.org/0000-0003-3627-214X
Jakob TräubleDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.
Stefan JokielFaculty of Physics, Ludwig Maximilian University of Munich, Munich, Germany.
Raphael LermerInstitute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Lucas Paulo de Lima CamilloSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-8166-0761
Korbinian TraeubleInstitute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.ORCID http://orcid.org/0009-0009-1413-3115
Biomarkers of Aging Consortium
Dane GobelMethuselah Foundation, Washington, DC, USA.
Chiara HerzogInstitute for Biomedical Ageing Research, Universität Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-1572-498X
Matthias HeinigInstitute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.
Heribert SchunkertCardiology, Deutsches Herzzentrum München, Klinikum der Technischen Universität München, Munich, Germany.
Gabriele S Kaminski SchierleDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.
Jesse R PoganikDivision of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-3098-8550
Mahdi MoqriDivision of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. mmoqri@bwh.harvard.edu.ORCID http://orcid.org/0000-0001-6675-0566
Vadim N GladyshevDivision of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. vgladyshev@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-0372-7016

Funding

QUANTITATIVE ASSESSMENT OF BIOLOGICAL AGE AND ITS APPLICATIONSR01AG065403 · NIA · YALE UNIVERSITY · PI Vadim N. Gladyshev, Albert Tzongyang Higgins-Chen · 2020 to 2026
$4.2M
Using causal aging biomarkers and protein design to develop novel anti-aging interventionsK00AG088431 · NIA · STANFORD UNIVERSITY · PI Kejun Ying · 2025 to 2026
$176k
Using causal aging biomarkers and protein design to develop novel anti-aging interventionsF99AG088431 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI YING, KEJUN · 2024 to 2024
$37k
NIA NIH HHS F99 AG088431NIA NIH HHS K00 AG088431NIA NIH HHS R01 AG065403U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) AG065403U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) AG088431
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42277290
PMCPMC13476092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.