Evidence map›Paper›PMID 42277172›Full record

ArticleScientific reports2026

Development and validation of the Life after Stroke questionnaire as a patient-reported outcome measure for stroke survivors living at home.

Wolfgang Brunner, Christoph Zenzmaier, Nina Huber, Julian Granna, Kurt Mölgg, Benjamin Dejakum, Silvia Felicetti, Anel Karisik, Stefan Kiechl, Christian Boehme and 1 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wolfgang BrunnerHealth University of Applied Sciences Tyrol, Innrain 98, Innsbruck, 6020, Austria. wolfgang.brunner@fhg-tirol.ac.at.
Christoph ZenzmaierHealth University of Applied Sciences Tyrol, Innrain 98, Innsbruck, 6020, Austria.
Nina HuberHealth University of Applied Sciences Tyrol, Innrain 98, Innsbruck, 6020, Austria.
Julian GrannaCenter on Clinical Stroke Research, VASCage, Innsbruck, Austria.
Kurt MölggCenter on Clinical Stroke Research, VASCage, Innsbruck, Austria.
Benjamin DejakumCenter on Clinical Stroke Research, VASCage, Innsbruck, Austria.
Silvia FelicettiCenter on Clinical Stroke Research, VASCage, Innsbruck, Austria.
Anel KarisikCenter on Clinical Stroke Research, VASCage, Innsbruck, Austria.
Stefan KiechlCenter on Clinical Stroke Research, VASCage, Innsbruck, Austria.
Christian BoehmeDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Michael KnoflachCenter on Clinical Stroke Research, VASCage, Innsbruck, Austria.

Funding

Österreichische Forschungsförderungsgesellschaft 898252
6 · The paper itself

Abstract

Cerebrovascular disease is a leading cause of death and permanent neurological impairment worldwide. The goal of this study is to develop and validate a patient-reported outcome measure (PROM) that evaluates the daily lives of stroke survivors living at home. The questionnaire was developed using a four-phase procedure based on guidelines from the European Organization for Research and Treatment of Cancer Quality of Life Group. The phases included a literature review, semi-structured interviews with stroke patients, construction of the questionnaire, pre-testing with 20 patients, and validation with 216 patients. The statistical analyses included descriptive statistics, the intraclass correlation coefficient (ICC), Cronbach's alpha, and Spearman's rank correlation coefficients. The questionnaire demonstrated high test-retest reliability and strong correlations with established measures (SIS and EQ-5D-3L). The final questionnaire covered topics such as independence in daily activities, psychological and social well-being, and quality of life. The developed PROM "Life after Stroke" is a comprehensive and practical tool for evaluating the lives of stroke survivors who live at home. Its validity and reliability make it suitable for research and routine assessments (initial assessment and documentation of progress in long-term care) by healthcare providers.Trial registration: The study was registered in the German Clinical Trials Register (DRKS Deutsches Register Klinischer Studien) on September 1st, 2022 (DRKSID DRKS00029484).

Indexed as

Patient Reported Outcome MeasuresQuality of LifeStrokeSurvivorsActivities of Daily LivingAgedAged, 80 and overFemaleHumansMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesHealthcare providersLife after strokePatient reported outcome measure (prom)QuestionnaireStroke

Identifiers

PMID42277172
PMCPMC13503800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.