Microwave-induced modulation of intracellular distribution of peptides based on mitochondrial targeting sequences.

Fumihiro Kayamori, Takuto Kariya, Momo Hirata, Yonejiro Arimoto, Tamaki Endoh, Nobuhiro Nakanishi, Kenji Usui

Abstract read

In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fumihiro KayamoriFaculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, Japan. kayamori@konan-u.ac.jp.

Takuto KariyaFaculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, Japan.

Momo HirataFaculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, Japan.

Yonejiro ArimotoFaculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, Japan.

Tamaki EndohGraduate School of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, Japan.

Nobuhiro NakanishiResearch Institute for Nanobio-environment and Non-Ionizing Radiation (RINNIR), Konan University, Kobe, Japan.

Kenji UsuiFaculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, Kobe, Japan. kusui@konan-u.ac.jp.

Funding

Japan Science and Technology Agency JPMJCR21B2

6 · The paper itself

Abstract

Microwave (MW) irradiation has recently emerged as a promising physical approach for modulating the intracellular behavior of bioactive molecules. However, its potential effects on intracellular distribution and spatial association remain largely unexplored. In this study, we investigated MW-induced changes in the intracellular distribution of peptides designed based on previously reported mitochondrial targeting sequences under MW irradiation at 2.45 GHz. Peptide-derived fluorescence and its intracellular distribution were analyzed using confocal laser scanning microscopy and flow cytometry. MW irradiation induced sequence-dependent changes in cellular fluorescence intensity, with (Cha-r)

Indexed as

MicrowavesMitochondriaPeptidesAmino Acid SequenceCell SurvivalHeLa CellsHumansMicroscopy, ConfocalPeptides2.45 GHzcellular uptakeintracellular distributionmicrowavemitochondrial targeting sequencespeptides

Identifiers

PMID42277135

DOI10.1038/s41598-026-55313-2

PMCPMC13507107

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.