Evidence map›Paper›PMID 42277116›Full record

ArticleScientific reports2026

Identification of key candidate genes for body weight traits in male Dongfeng sika deer based on genome-wide association analysis.

Xinyuan Zhang, Yan Zhang, Lieping Zhao, Yao Zhao, Wen-Xi Qian, Guanghui Gai, Jun Song, Peize Du, Huansheng Han, Zhen Zhang

Abstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinyuan ZhangCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, 163319, China.ORCID http://orcid.org/0009-0006-7133-654X
Yan ZhangCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, 163319, China.ORCID http://orcid.org/0009-0006-2256-5055
Lieping ZhaoHeilongjiang Academy of Agricultural Reclamation Sciences, Harbin, 150000, China.ORCID http://orcid.org/0009-0005-1356-3157
Yao ZhaoCollege of Life Sciences and Technology, Harbin Normal University, Harbin, 150000, China.ORCID http://orcid.org/0000-0002-4405-8592
Wen-Xi QianCollege of Animal Science and Technology, Tarim University, Alar, 843300, China.ORCID http://orcid.org/0009-0009-9859-7194
Guanghui GaiInner Mongolia Genhe Forest Industry Co., Ltd, Genhe, 022350, China.ORCID http://orcid.org/0009-0007-8441-5033
Jun SongDongfeng County Deer Industry Development Service Center, Liaoyuan City, 136300, China.ORCID http://orcid.org/0009-0004-7809-6054
Peize DuCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, 163319, China.ORCID http://orcid.org/0009-0003-2497-9735
Huansheng HanCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, 163319, China. 13895726439@163.com.ORCID http://orcid.org/0000-0002-4106-9245
Zhen ZhangHeilongjiang Academy of Agricultural Reclamation Sciences, Harbin, 150000, China. dongnongzz@126.com.ORCID http://orcid.org/0000-0002-3305-7666

Funding

the Emergency collection of endangered special animal germplasm resources - frozen semen of deer NSTI-ANGR-2021-03the Inner Mongolia Forestry Industry Group Science and Technology Project GSKJ-2023001the Tarim Animal Husbandry Science and Technology Corps Key Laboratory HS202501
6 · The paper itself

Abstract

This study aimed to identify genetic markers for body weight in adult male Dongfeng sika deer (Cervus nippon) using a genome-wide association study (GWAS). A cohort of 266 healthy, five-year-old stags was phenotyped and genotyped via whole-genome resequencing. Population structure was assessed, and a mixed linear model (MLM) was employed for association testing, followed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of candidate genes. The GWAS identified twelve genome-wide significant SNP loci, which were annotated to seven candidate genes: ERC2, LOC122708028, FHIT, CASP14, UBE3A, NRXN3, and GABRA5. Functional enrichment analyses revealed these genes are significantly involved in the γ-aminobutyric acid (GABA)ergic synaptic transmission pathway and pathways related to DNA damage repair and cell cycle regulation. This study provides insights into the genetic mechanisms underlying body weight traits in adult male Dongfeng sika deer and offers a reference for subsequent functional exploration of candidate genes.

Indexed as

Body WeightDeerGenome-Wide Association StudyAnimalsGene OntologyGenotypeMalePhenotypePolymorphism, Single NucleotideBody weightCandidate genesDongfeng sika deerGene ontology and KEGG analysesGWASMolecular breeding

Identifiers

PMID42277116
PMCPMC13507383

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.