Evidence map›Paper›PMID 42276987›Full record

ArticleBone research2026

JMJD3-driven epigenetic reprogramming of p16

Xiaonan Liu, Wenhao Lu, Yicheng Wang, Peilin Zhang, Zhongyi Su, Ting Cao, Yifei Zhang, Junjie Zhao, Jiayi Wang, Hulin Xiang and 6 more

Abstract read
In one paragraph

Article in Bone research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xiaonan Liu *Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.ORCID 0000-0003-3661-7961
Wenhao Lu *Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, PR China.
Yicheng Wang *Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Peilin ZhangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Zhongyi SuDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Ting CaoDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.ORCID 0000-0003-3529-2923
Yifei ZhangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Junjie ZhaoDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Jiayi WangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Hulin XiangHainan Academy of Medical Sciences, Hainan Medical University, Haikou, Hainan, PR China.
Weijun HuangDepartment of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, PR China.
Kai WangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Sa PangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Minkai ChenDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Yusheng LiDepartment of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, PR China. liyusheng@csu.edu.cn.ORCID 0000-0002-3404-0807
Shen LiuDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. liushensjtu@126.com.

Funding

National Natural Science Foundation of China (National Science Foundation of China) No.82302740
6 · The paper itself

Abstract

Tendon healing is a complex biological process that involves inflammation, cellular reprogramming, and extracellular matrix (ECM) remodeling. The cyclin-dependent kinase inhibitor p16

Indexed as

Achilles TendonCyclin-Dependent Kinase Inhibitor p16Epigenesis, GeneticJumonji Domain-Containing Histone DemethylasesRegenerationTendon InjuriesAnimalsExtracellular MatrixMaleMiceMice, Inbred C57BLCyclin-Dependent Kinase Inhibitor p16Jumonji Domain-Containing Histone DemethylasesKdm6b protein, mouse

Identifiers

PMID42276987
PMCPMC13261133

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.