Evidence map›Paper›PMID 42276787›Full record

ArticleeNeuro2026

Characterization of Neuronal Ensembles in a Model of Dual-Reward Conditioned Place Preference.

Levi T Flom, Kathryn L Sandum, Skylar L Hodgins, Samuel Johnson Noya, Jenna Crouse, Zhaojie Zhang, Ana-Clara Bobadilla

Abstract read
In one paragraph

Article in eNeuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Levi T FlomDepartment of Biomedical Sciences, Colorado State University, Fort Collins, Colorado.ORCID https://orcid.org/0009-0003-6275-6540
Kathryn L SandumSchool of Pharmacy, University of Wyoming, Laramie, Wyoming.
Skylar L HodginsSchool of Pharmacy, University of Wyoming, Laramie, Wyoming.ORCID https://orcid.org/0000-0001-5420-9174
Samuel Johnson NoyaSchool of Pharmacy, University of Wyoming, Laramie, Wyoming.
Jenna CrouseSchool of Pharmacy, University of Wyoming, Laramie, Wyoming.
Zhaojie ZhangDepartment of Zoology and Physiology, University of Wyoming, Laramie, Wyoming.ORCID https://orcid.org/0000-0001-6790-6243
Ana-Clara BobadillaDepartment of Biomedical Sciences, Colorado State University, Fort Collins, Colorado ac.bobadilla@colostate.edu.ORCID https://orcid.org/0000-0002-4273-1237

Funding

Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI Nicolas A. Blouin · 2012 to 2026
$56.8M
Zebrafish Models of CNS Injury and Locomotor RecoveryP20GM121310 · NIGMS · UNIVERSITY OF WYOMING · PI Qian-Quan Sun · 2017 to 2026
$27.2M
Nucleus accumbens neuronal ensembles in drugs and natural rewards seeking.R00DA046522 · NIDA · UNIVERSITY OF WYOMING · PI BATCHELDER, ABIGAIL · 2021 to 2023
$812k
NIDA NIH HHS R00 DA046522NIGMS NIH HHS P20 GM103432NIGMS NIH HHS P20 GM121310
6 · The paper itself

Abstract

Substance use disorder is characterized by maladaptive patterns of reward-seeking behavior. Such behavior has been linked to neuronal ensembles, typically identified through activity-dependent expression. These ensembles have been studied in regions such as the prelimbic prefrontal cortex and the nucleus accumbens core. In this study, we characterized ensembles tagged during concurrent exposure to cocaine- and chocolate-associated contexts. We used 33 male and 33 female Ai14xFos

Indexed as

Conditioning, PsychologicalNeuronsNucleus AccumbensPrefrontal CortexRewardAnimalsChocolateCocaineDopamine Uptake InhibitorsFemaleMaleMiceMice, TransgenicProto-Oncogene Proteins c-fosCocaineDopamine Uptake InhibitorsProto-Oncogene Proteins c-fosc-Fos-TRAP2chocolatecocainedual-rewardneuronal ensemblesnucleus accumbens coreprefrontal cortex

Identifiers

PMID42276787
PMCPMC13312911

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.