Evidence map›Paper›PMID 42275976›Full record

ArticleJournal of optometry

Impact of peripheral optical errors in age-related macular degeneration.

Abinaya Priya Venkataraman, Robert Rosén, Marrie van der Mooren, Aixa Alarcón Heredia, Dmitry Romashchenko, Carmen Cánovas Vidal, Linda Lundström

Abstract read
In one paragraph

Article in Journal of optometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abinaya Priya VenkataramanDepartment of Applied Physics, KTH (Royal Institute of Technology), Sweden.
Robert RosénJohnson & Johnson Vision, R&D, Groningen, Netherlands.
Marrie van der MoorenJohnson & Johnson Vision, R&D, Groningen, Netherlands.
Aixa Alarcón HerediaJohnson & Johnson Vision, R&D, Groningen, Netherlands.
Dmitry RomashchenkoJohnson & Johnson Vision, R&D, Groningen, Netherlands.
Carmen Cánovas VidalJohnson & Johnson Vision, R&D, Groningen, Netherlands.
Linda LundströmDepartment of Applied Physics, KTH (Royal Institute of Technology), Sweden. Electronic address: linda@biox.kth.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAge-related macular degeneration (AMD) is a common ocular condition leading to reduced central visual function and increased dependency on the peripheral field of view for all visual tasks. This study aims to assess the effect of optical errors on peripheral vision in dry form AMD.

methodsHigh contrast resolution acuity and contrast sensitivity were measured in the 20° nasal visual field of fourteen subjects with advanced or early dry AMD. The measurements were performed through an adaptive optics vision simulator to simulate average phakic as well as pseudophakic peripheral optical errors.

resultsOverall, inducing population average phakic optical errors resulted in better peripheral visual function than average pseudophakic optical errors for all measured subjects, both in high contrast resolution acuity and contrast sensitivity. Specifically, the mean differences between phakic and pseudophakic conditions were 0.16 logMAR in resolution acuity and 0.43 in logarithmic contrast sensitivity. These changes are larger than the results of studies on younger subjects with healthy vision.

conclusionThe study thereby concludes that reducing peripheral optical errors can improve peripheral vision, although further work is needed to determine how this translates to everyday visual performance. Interestingly, the improvement appears to be larger for AMD patients compared to healthy eyes.

Indexed as

Contrast SensitivityGeographic AtrophyMacular DegenerationPseudophakiaVisual AcuityVisual FieldsAgedAged, 80 and overFemaleHumansMaleMiddle AgedAge-related macular degenerationContrast sensitivityOff-axis aberrationsPeripheral visionPhakic vs Pseudophakic opticsResolution acuity

Identifiers

PMID42275976
PMCPMC13273818

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.