Evidence map›Paper›PMID 42275225›Full record

ArticleSTAR protocols2026

Protocol for co-culture of murine bone marrow-derived dendritic cells with OT-I mouse CD8

Min Jiang, Dana Matzek, Anny Nguyen, Bastian Popper, Olivia M Merkel

Abstract read
In one paragraph

Article in STAR protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Min JiangLudwig-Maximilians-Universität München, Department of Pharmacy, Butenandtstraße 5, 81377 Munich, Germany; Member of the German Center for Lung Research (DZL), Munich, Germany. Electronic address: min.jiang@cup.uni-muenchen.de.
Dana MatzekLudwig-Maximilians-Universität München, Biomedical Center, Großhaderner Str. 9, 82152 Planegg- Martinsried, Germany; Ludwig-Maximilians-Universität München, Core Facility Animal Models, Großhaderner Str. 9, 82152 Planegg- Martinsried, Germany.
Anny NguyenLudwig-Maximilians-Universität München, Department of Pharmacy, Butenandtstraße 5, 81377 Munich, Germany.
Bastian PopperLudwig-Maximilians-Universität München, Biomedical Center, Großhaderner Str. 9, 82152 Planegg- Martinsried, Germany; Ludwig-Maximilians-Universität München, Core Facility Animal Models, Großhaderner Str. 9, 82152 Planegg- Martinsried, Germany.
Olivia M MerkelLudwig-Maximilians-Universität München, Department of Pharmacy, Butenandtstraße 5, 81377 Munich, Germany; Center for Nanoscience (CeNS) Munich, Munich, Germany; Cluster for Nucleic Acid Therapeutics Munich (CNATM), Munich, Germany. Electronic address: olivia.merkel@lmu.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preliminary evaluation of vaccine-induced immune activation can be performed with minimal animal use, in line with the principles of the 3Rs (replacement, reduction, and refinement) in animal experimentation. Here, we present a protocol to assess murine antigen-specific CD8

Indexed as

Bone Marrow CellsCD8-Positive T-LymphocytesDendritic CellsAnimalsCoculture TechniquesLymphocyte ActivationMiceMice, TransgenicCell-based AssaysHealth SciencesImmunologyModel Organisms

Identifiers

PMID42275225
PMCPMC13273787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.