Evidence map›Paper›PMID 42274946›Full record

ArticleJournal of racial and ethnic health disparities2026

Language, Immigration, Race and Cognitive Health: Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study.

Elisa Lee, Rachel A Whitmer, Paola Gilsanz, Claire C Meunier, Yi Lor, Nancy X Chen, Kristen M George

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Article in Journal of racial and ethnic health disparities, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Elisa LeeDepartment of Public Health Sciences, University of California Davis, Davis, CA, USA.
Rachel A WhitmerDepartment of Public Health Sciences, University of California Davis, Davis, CA, USA.
Paola GilsanzKaiser Permanente Division of Research, Pleasanton, CA, USA.
Claire C MeunierDepartment of Public Health Sciences, University of California Davis, Davis, CA, USA.
Yi LorDepartment of Public Health Sciences, University of California Davis, Davis, CA, USA.
Nancy X ChenDepartment of Public Health Sciences, University of California Davis, Davis, CA, USA.
Kristen M GeorgeDepartment of Public Health Sciences, University of California Davis, Davis, CA, USA. krmgeorge@health.ucdavis.edu.ORCID http://orcid.org/0000-0001-8773-7678

Funding

Lifecourse health, cerebral pathology and ethnic disparities in dementia (KHANDLE Study)R01AG052132 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GILSANZ, PAOLA, GLYMOUR, MEDELLENA MARIA · 2021 to 2025
$18.0M
The Role of Lipids in Alzheimer's Disease and Related Dementias among Black Americans: Examining Lifecouse MechanismsK01AG081499 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Kristen M George · 2023 to 2026
$497k
NIA NIH HHS K01 AG081499NIA NIH HHS K01AG081499NIA NIH HHS R01 AG052132NIA NIH HHS R01AG052132
6 · The paper itself

Abstract

backgroundFew large cohort studies of dementia have successfully recruited cohorts that reflect the diversity of the aging population. We aim to describe the complex racial/ethnic, immigration, linguistic histories of a United States (US)-based cohort to describe the complexity of operationalizing identity and describing health disparities.

methodsThe Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study enrolled 1,892 participants ages 65 and older. Participants self-reported race/ethnicity (Asian, Black, Latino, White, Native American), immigration status (US-born/non-US-born), and languages spoken (monolingual, bilingual, and unascertained) via questionnaire. Participants were screened using NIH Toolbox and those suspected of impairment underwent a neurological exam. Descriptive statistics included means, standard deviations, counts, and percentages of cohort demographics across race/ethnicity, immigration status, and language as well as by cognitive status.

resultsParticipants had a mean age of 76 (SD ± 7) and 60% were women. Approximately equal proportions of Asian (24%), Black (26%), Latino (22%), Native American (0.1%), and White (29%) participants were enrolled. 46% of participants were monolingual, 31% bilingual, and 23% unascertained. Of the 25% of participants who reported being non-US-born, most identified as Asian or Latino. Bilingualism was most common among non-US-born men and those reporting multiple racial/ethnic identities. Alcohol consumption, cigarette use, and self-rated health varied across language, race/ethnicity, and immigration status. Cognitive impairment was most prevalent among U.S.-born Black and non-U.S.-born Latino participants.

conclusionHighlighting the diversity of older Americans illustrates the need for recruitment of populations that reflect the cultural and linguistic diversity of older adults in the US at risk of dementia.

Indexed as

CognitionHealth disparitiesImmigrationLanguageRace

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.