Evidence map›Paper›PMID 42274917›Full record

ArticleJapanese journal of radiology2026

Nationwide organ volume distributions and cross-sectional age-associated differences in abdominal CT from Japan.

Tomohiro Kikuchi, Kohei Yamamoto, Yosuke Yamagishi, Toshiaki Akashi, Shouhei Hanaoka, Takeharu Yoshikawa, Hiroyuki Fujii, Harushi Mori, Hisaki Makimoto, Takahide Kohro

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tomohiro KikuchiData Science Center, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan. r1419kt@jichi.ac.jp.ORCID http://orcid.org/0000-0002-4222-4569
Kohei YamamotoDepartment of Radiology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Yosuke YamagishiDivision of Radiology and Biomedical Engineering, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Toshiaki AkashiDepartment of Radiology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-Ku, Tokyo, 113-8421, Japan.
Shouhei HanaokaDepartment of Radiology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Takeharu YoshikawaDepartment of Computational Diagnostic Radiology and Preventive Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Hiroyuki FujiiDepartment of Radiology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Harushi MoriDepartment of Radiology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Hisaki MakimotoData Science Center, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Takahide KohroData Science Center, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.

Funding

Cross-ministerial Strategic Innovation Promotion Program JPJ012425Japan Society for the Promotion of Science JP23K17234
6 · The paper itself

Abstract

purposeLarge-scale CT-based reference distributions for abdominal organ volume that incorporate age, sex, and body size are limited. To establish sex- and age-specific reference distributions for major abdominal organ volumes on non-contrast abdominopelvic CT in a nationwide Japanese cohort to provide a foundation for automated clinical assessment. MATERIALS AND

methodsIn this retrospective, multicenter study, we used the Japan Medical Image Database to identify all non-contrast abdominopelvic CT examinations performed in 2024. Unique adults with available data on age, sex, height, and weight were included in this study. The final sample comprised 49,764 examinations (26,456 men and 23,308 women) conducted at nine different institutions. Automated segmentation (TotalSegmentator v2.10.0) was used to produce organ volumes, excluding the hollow viscera. Sex-specific 10th, 25th, 50th, 75th, and 90th percentiles were calculated. Age-volume relationships of body surface area (BSA)-normalized volumes (mL/m

resultsThe median male vs. female volumes (mL) were as follows: liver, 1,194.7 vs 1,024.0; pancreas, 63.7 vs 52.3; spleen, 118.7 vs 95.4; kidneys (total), 268.3 vs 221.2; adrenals (total), 6.7 vs 4.2; iliopsoas (total), 483.4 vs 317.7; and prostate, 25.5 (men only). The age-volume relationships of BSA-normalized volumes showed convex patterns for the liver, pancreas, and kidneys in both sexes and for male adrenal glands; lower values in older age groups for the spleen and iliopsoas in both sexes; and higher values in older age groups for the prostate and female adrenal glands.

conclusionThis nationwide Japanese CT cohort provides sex- and age-resolved organ volume reference distributions. These distributions may serve as a quantitative reference for clinical interpretation and population-based imaging research.

Indexed as

AbdomenRadiography, AbdominalTomography, X-Ray ComputedAdultAgedAged, 80 and overAge FactorsFemaleHumansJapanMaleMiddle AgedOrgan SizeReference ValuesRetrospective StudiesSex FactorsAbdomenComputed tomographyOrgan volumeReference valuesSegmentation

Identifiers

PMID42274917
PMCPMC13623781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.