Evidence map›Paper›PMID 42274870›Full record

ReviewBlood research2026

Infectious complications after CAR T-cell therapy: mechanisms, risk stratification, and prevention.

Eunseuk Lee, Ji Hyun Lee, Hye Ryeon Kim, Seok Jae Huh, Suee Lee, Sung-Yong Oh, Sung-Hyun Kim, Hojin Lee

Abstract readReview
In one paragraph

Review in Blood research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eunseuk LeeDepartment of Internal Medicine, The State University of New Jersey, Rutgers, NJ, USA.
Ji Hyun LeeDivision of Hematology-Oncology, Department of Internal Medicine, Dong-A University College of Medicine, 26, Daeshingongwon-Ro, Seo-Gu, Busan, 49201, Republic of Korea. hidrleejh12@gmail.com.
Hye Ryeon KimDivision of Hematology-Oncology, Department of Internal Medicine, Dong-A University College of Medicine, 26, Daeshingongwon-Ro, Seo-Gu, Busan, 49201, Republic of Korea.
Seok Jae HuhDivision of Hematology-Oncology, Department of Internal Medicine, Dong-A University College of Medicine, 26, Daeshingongwon-Ro, Seo-Gu, Busan, 49201, Republic of Korea.
Suee LeeDivision of Hematology-Oncology, Department of Internal Medicine, Dong-A University College of Medicine, 26, Daeshingongwon-Ro, Seo-Gu, Busan, 49201, Republic of Korea.
Sung-Yong OhDivision of Hematology-Oncology, Department of Internal Medicine, Dong-A University College of Medicine, 26, Daeshingongwon-Ro, Seo-Gu, Busan, 49201, Republic of Korea.
Sung-Hyun KimDivision of Hematology-Oncology, Department of Internal Medicine, Dong-A University College of Medicine, 26, Daeshingongwon-Ro, Seo-Gu, Busan, 49201, Republic of Korea.
Hojin LeeDivision of Infectious Disease, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chimeric antigen receptor (CAR) T-cell therapy is an established treatment for relapsed or refractory B-cell malignancies. Despite therapeutic success, infectious complications remain a major contributor to non-relapsed morbidity and mortality. The risk of infection reflects a prolonged and multifactorial state of immunosuppression resulting from lymphodepleting chemotherapy, treatment-related cytopenia, sustained CD4

Indexed as

Antimicrobial prophylaxisCAR T-cell therapyHypogammaglobulinemiaImmunodeficiencyInfectionVaccination

Identifiers

PMID42274870
PMCPMC13260542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.