Evidence map›Paper›PMID 42274843›Full record

ArticleBiochemical genetics2026

HILPDA, Regulated by WTAP in an m6A-Dependent Manner, Enhances Osteosarcoma Development by Inhibiting Ferroptosis and Promoting Glycolysis.

Yong Jing, Guoyong Zhang, Chenghui Sun, Yawei Pan, Jun Tuo, Zhi Li, Chengji Jiang, Zejian Qiu, Qin Lou

Abstract read
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In one paragraph

Article in Biochemical genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yong Jing *Department of Orthopedics, Shiqian County People's Hospital, Tongren, Guizhou, China.
Guoyong Zhang *Department of Onco-Hematology and Peripheral Interventional Radiology, Shiqian County People's Hospital, Tongren, Guizhou, China.
Chenghui SunDepartment of Oncology and Hematology, Houjie Hospital of Dongguan, Dongguan, 523962, Guangdong, China. 13431165368@163.com.
Yawei PanDepartment of Spine and Joint Surgery, Kanghua Hospital of Dongguan, Dongguan, Guangdong, China.
Jun TuoDepartment of Onco-Hematology and Peripheral Interventional Radiology, Shiqian County People's Hospital, Tongren, Guizhou, China.
Zhi LiDepartment of Onco-Hematology and Peripheral Interventional Radiology, Shiqian County People's Hospital, Tongren, Guizhou, China.
Chengji JiangDepartment of Onco-Hematology and Peripheral Interventional Radiology, Shiqian County People's Hospital, Tongren, Guizhou, China.
Zejian QiuDepartment of Onco-Hematology and Peripheral Interventional Radiology, Shiqian County People's Hospital, Tongren, Guizhou, China.
Qin LouDepartment of Onco-Hematology and Peripheral Interventional Radiology, Shiqian County People's Hospital, Tongren, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is the most common primary malignant bone cancer. Hypoxia-inducible lipid droplet-associated protein (HILPDA) promotes tumor growth, migration, and ferroptosis resistance in OS. However, the oncogenic mechanisms of HILPDA in OS are largely unexplored. Glycolytic activity was assessed by measuring glucose uptake and lactate release. Ferroptosis was evaluated by measuring ROS, MDA, Fe

Indexed as

Bone NeoplasmsCell Cycle ProteinsFerroptosisGlycolysisOsteosarcomaRNA Splicing FactorsAnimalsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansMiceMice, NudeRNA MethylationCell Cycle ProteinsRNA Splicing FactorsWTAP protein, humanFerroptosisGlycolysisHypoxia-inducible lipid droplet-associated proteinM6A ModificationOsteosarcoma

Identifiers

PMID42274843

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.