Evidence map›Paper›PMID 42274736›Full record

SynthesisSocial psychiatry and psychiatric epidemiology2026

Cognitive remediation therapy in low-and-middle-income countries (LAMICs) for people with psychosis: a systematic review of its efficacy on functional and cognitive outcomes.

Yamini Vig, Yohannes Gebreegziabher, Charlotte Hanlon, Matteo Cella

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in Social psychiatry and psychiatric epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yamini VigInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0009-0001-9288-5939
Yohannes GebreegziabherDepartment of Psychiatry, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Charlotte HanlonDepartment of Psychiatry, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID http://orcid.org/0000-0002-7937-3226
Matteo CellaInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. matteo.cella@kcl.ac.uk.ORCID http://orcid.org/0000-0002-5701-0336

Funding

Wellcome Trust
6 · The paper itself

Abstract

purposeCognitive difficulties are commonly present in people with psychosis and are associated with poor functional outcomes. Evidence from high-income countries (HICs) indicates that cognitive remediation (CR) is an effective treatment for cognitive difficulties. Evidence from low and middle-income countries (LAMICs) is emerging. This study reviews the evidence for CR for people with psychosis in LAMICs.

methodsSeven databases (GIM, SCOPUS, WoS, APA PsycINFO, Global Health, Medline(R), and Embase) were searched. Two reviewers screened the studies retrieved independently against the eligibility criteria. Risk of bias was assessed using ROB 2.0 and ROBINS-I. The results on CR efficacy, alongside application and delivery, were synthesised narratively.

resultsFourteen studies from countries in Africa, Asia and South America were included. CR delivery modality and settings varied, including those delivered at home and by caregivers and health care workers. Thirteen studies showed that CR was beneficial for cognition, with small to large effect sizes. Nine studies showed that CR can improve functioning, with small to moderate effect sizes. The studies showed that CR was safe and well-tolerated. The effect of CR did not differ by setting, dosage, delivery agent or mode of delivery.

conclusionsCR could be a useful approach to reduce the burden of cognitive difficulties in people with psychosis in LAMIC. The adaptations to CR evaluated by the included studies could be used and further evaluated globally to provide novel, culturally acceptable and scalable implementation approaches for CR.

Indexed as

Cognitive RemediationDeveloping CountriesPsychotic DisordersAfricaAsiaHumansTreatment OutcomeCognitionCognitive remediationLow- and middle-income countriesPsychosisSevere mental illnessSystematic review

Identifiers

PMID42274736
PMCPMC13522050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.