Evidence map›Paper›PMID 42274612›Full record

ArticleCells2026

Functional Profile of γδ T Cells in Severe and Moderate COVID-19: A Brazilian Cross-Sectional Study.

Andressa da Silva Cazote, Glenda Domingos Mascarenhas, Hugo Perazzo, Kim Mattos Geraldo, Maria Pia Diniz Ribeiro, Juliana Arruda de Matos, Pedro Emmanuel Alvarenga Americano do Brasil, Sandra Wagner Cardoso, Beatriz Grinsztejn, Valdiléa Gonçalves Veloso and 9 more

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Andressa da Silva CazoteLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0002-3775-6923
Glenda Domingos MascarenhasLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Hugo PerazzoInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Kim Mattos GeraldoInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Maria Pia Diniz RibeiroInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0001-7274-6838
Juliana Arruda de MatosInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Pedro Emmanuel Alvarenga Americano do BrasilInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0002-6700-2268
Sandra Wagner CardosoInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Beatriz GrinsztejnInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Valdiléa Gonçalves VelosoInstituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Cynthia Machado CascabulhoFlow Cytometry Platform-Multiparametric Analysis Unit, Oswaldo Cruz Institute, Rio de Janeiro 21040-360, Brazil.
José Henrique PilottoLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0003-0521-8597
Diogo Gama CaetanoLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0002-8889-0655
Milena Neira Guimarães GoulartLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Nathalia Beatriz Ramos de SáLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0002-1084-6435
Dalziza Victalina de AlmeidaLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0003-0917-0009
Fernanda Heloise CôrtesLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0003-1416-0657
Mariza Gonçalves MorgadoLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0002-9304-6184
Carmem Beatriz Wagner Giacoia-GrippLaboratório de AIDS & Imunologia Molecular, Instituto Oswaldo Cruz (IOC), FIOCRUZ, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0003-0424-5219

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro-FAPERJ SEI-260003/002689/2020Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro-FAPERJ SEI-260003/013002/2021INOVA FIOCRUZ/Fundação Oswaldo Cruz 48401996705881
6 · The paper itself

Abstract

This study aimed to identify the distinct intrinsic response potential of γδ T cells from COVID-19 patients with different illness severities, to better understand the implication of these cells in COVID-19 disease. Forty-four COVID patients were enrolled at hospitalization and classified as: moderate without oxygen support (MWO

Indexed as

COVID-19Receptors, Antigen, T-Cell, gamma-deltaT-LymphocytesAdultAgedBrazilCross-Sectional StudiesFemaleHumansInterleukin-17MaleMiddle AgedSARS-CoV-2Severity of Illness IndexInterleukin-17Receptors, Antigen, T-Cell, gamma-deltaCOVID-19disease severityγδ T cells

Identifiers

PMID42274612
PMCPMC13256624

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.