Evidence map›Paper›PMID 42274374›Full record

ArticleThe Journal of infectious diseases2026

Ranked Placement of Phage Predation as a Determinant of Dehydration Severity Among Cholera Patients in Bangladesh.

N Madi, Md Abu Sayeed, E T Cato, A Creasy-Marrazzo, K Islam, Md I U L Khabir, Md T Islam, Z H Khan, Md T R Bhuiyan, Y Begum and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

N MadiDepartment of Microbiology & Immunology, McGill University, Montréal, Quebec, Canada.ORCID 0000-0001-8793-7389
Md Abu SayeedDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.
E T CatoDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.
A Creasy-MarrazzoDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-8820-2218
K IslamInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0001-5557-4368
Md I U L KhabirInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Md T IslamInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Z H KhanInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0002-8526-4165
Md T R BhuiyanInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Y BegumInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
E FreemanDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.
A VustepalliDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.
L BrinkleyDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.
M KamatDepartment of Chemistry, University of Florida, Gainesville, Florida, USA.
L S BaileyDepartment of Chemistry, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-6415-8905
K B BassoDepartment of Chemistry, University of Florida, Gainesville, Florida, USA.ORCID 0000-0003-1268-6655
F QadriInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
A I KhanInfectious Diseases Division (IDD) & Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
B J ShapiroDepartment of Microbiology & Immunology, McGill University, Montréal, Quebec, Canada.ORCID 0000-0001-6819-8699
E J NelsonDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.ORCID 0000-0003-2649-2624

Funding

Acquisition of a Q Exactive HF Hybrid Quadrupole-OrbitrapS10OD021758 · OD · UNIVERSITY OF FLORIDA · PI BASSO, KARI B · 2017 to 2017
$600k
The evaluation of a mHealth platform for diarrheal disease decision support and real-time epidemiologyR21TW010182 · FIC · UNIVERSITY OF FLORIDA · PI KHAN, ASHRAFUL ISLAM, NELSON, ERIC JORGE · 2016 to 2017
$320k
Canadian Institutes for Health Research Project GrantChildren's Miracle NetworkDepartments of PediatricsFIC NIH HHS R21 TW010182NIH HHS R21TW010182NIH HHS S10 OD021758NIH HHS S10 OD021758-01A1University of Florida
6 · The paper itself

Abstract

Virulent bacteriophages (phages) can kill bacterial prey, potentially reducing burden of infection. In cholera, a high phage to Vibrio cholerae ratio is associated with mild dehydration, yet the relative importance of this ratio in disease severity remains unclear. We used machine learning to rank select host, microbial, and environmental factors as determinants of dehydration severity in over 600 cholera patients from across Bangladesh. We found the phage:pathogen ratio ranked among the top classifiers for mild dehydration, behind age and location. We advocate that phage predation be included as a key factor in cholera characterization for scientific, clinical, and epidemiological applications.

Indexed as

BacteriophagesCholeraDehydrationVibrio choleraeBangladeshHumansMachine LearningSeverity of Illness Indexantibioticsbacteriophagecholeradehydrationmachine learning

Identifiers

PMID42274374
PMCPMC13668366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.