ArticlemSphere2026
Two temperature-dependent membrane fluidity regimes in gram-positive bacteria.
Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Temperature changes directly affect the mobility of molecules within a biological membrane, increasing or decreasing its fluidity. Plasma membrane fluidity is a fundamental physical property that governs bacterial cell physiology, influencing processes such as protein function, respiration, and antibiotic uptake. It is widely accepted that bacteria actively maintain a constant membrane fluidity in response to temperature fluctuations to preserve membrane function. This process, known as membrane fluidity homeostasis, occurs through regulated remodeling of lipid composition. Here, we used an assay based on total internal reflection-fluorescence correlation spectroscopy to directly quantify membrane fluidity in the gram-positive model bacterium IMPORTANCE: Temperature changes affect the physical properties of the plasma membrane. Typically, a reduction in temperature causes a less fluid and thus more viscous, membrane. It has been long established that bacteria such as the model bacterium
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