Evidence map›Paper›PMID 42274242›Full record

ArticleApplied and environmental microbiology2026

The novel prophage lysin Lys1459 exhibits broad-spectrum antibacterial activity via triple-binding domain.

Xiangpeng Yang, Yuan Wang, Xingshuai Li, Yixuan Li, Jingyi Wang, Xinyue Li, Xiaoting Yao, Xuguang Ruan, Juan Wang, Bin Ye and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiangpeng Yang *College of Agriculture and Forestry, Linyi University, Linyi, China.ORCID 0009-0004-2242-8611
Yuan Wang *College of Agriculture and Forestry, Linyi University, Linyi, China.
Xingshuai LiCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Yixuan LiCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Jingyi WangCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Xinyue LiCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Xiaoting YaoCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Xuguang RuanCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Juan WangCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Bin YeCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Jianrui NiuCollege of Agriculture and Forestry, Linyi University, Linyi, China.
Xinglin ZhangCollege of Agriculture and Forestry, Linyi University, Linyi, China.ORCID 0000-0001-6108-9326
Junfei MaCollege of Agriculture and Forestry, Linyi University, Linyi, China.ORCID 0009-0009-1742-6079

Funding

the Development Plan of the Youth Innovation Team in Colleges and Universities of Shandong Province 2023KJ355the Project of High-Tech SMES Innovation Improvement of Shandong Province 2025TSGCCZZB0817
6 · The paper itself

Abstract

Phage-encoded lysins represent a promising class of antimicrobial agents against drug-resistant bacteria due to their ability to degrade bacterial cell walls. This study characterizes a novel prophage-derived lysin, Lys1459, from IMPORTANCE: A three-domain lysin, Lys1459, was identified in

Indexed as

Anti-Bacterial AgentsProphagesStreptococcal InfectionsStreptococcusViral ProteinsAnimalsBacteremiaMiceStreptococcus agalactiaeStreptococcus PhagesAnti-Bacterial AgentsViral Proteinsbacteremia modellytic enzymeStreptococcustriple-binding activity

Identifiers

PMID42274242
PMCPMC13390383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.