Evidence map›Paper›PMID 42273768›Full record

ReviewRegenerative medicine

Ethical, legal, and social issues associated with human fetal tissue research in Japan.

Misao Fujita, Kyoko Akatsuka, Akane Hashimoto, Mari Honda, Tsunakuni Ikka, Minori Kokado, Yoshichika Mori, Masanori Oikawa, Go Okui, Mitinori Saitou and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Regenerative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Misao FujitaCenter for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.ORCID 0000-0001-7919-5362
Kyoko AkatsukaCenter for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Akane HashimotoDepartment of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan.
Mari HondaCollege of Engineering, Shibaura Institute of Technology, Saitama, Japan.
Tsunakuni IkkaDivision of Bioethics & Healthcare Law, Institute for Cancer Control, National Cancer Center Japan, Tokyo, Japan.
Minori KokadoGraduate School of Humanities, The University of Osaka, Osaka, Japan.
Yoshichika MoriFaculty of Management, Hannan University, Osaka, Japan.
Masanori OikawaDepartment of Medical Ethics, Tohoku University Graduate School of Medicine, Sendai-shi, Japan.
Go OkuiGraduate School of Humanities and Faculty of Letters, Kobe University, Kobe-shi, Japan.
Mitinori SaitouCenter for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Yasuhiro TakashimaCenter for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Informed Consent Standards for Human Fetal Tissue Donation for Research, published by the International Society for Stem Cell Research, provide important guidance for ethical research. They are particularly relevant in countries such as Japan, where clear legal frameworks for the use of human fetal and associated tissues obtained through induced abortion are lacking. However, because such guidelines do not fully account for national regulatory and legal frameworks, additional considerations are required to support their effective global implementation. Here, we describe three ethical, legal, and social issues in Japan - also shared in part by other countries - as examples of considerations relevant to the wider implementation of internationally recognized ethical standards. We discuss possible approaches to these issues, including: (1) appropriate selection of medical institutions capable of minimizing the burden on potential donors, (2) consideration of whether consent from the male partner should be obtained, and (3) clarification of the "Ena (placenta)" ordinance related to the use and disposal of dead fetuses. Ensuring appropriate integration between such ethical standards and local regulations is essential for the sustainable and ethical development of fetal tissue research.

Indexed as

Fetal ResearchFetusFemaleHumansInformed ConsentJapanfetal tissue donationHuman fetal tissue researchinformed consentJapanregulatory governance

Identifiers

PMID42273768
PMCPMC13540158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.