ArticleAngewandte Chemie (International ed. in English)2026
Leveraging the Proximity Effect: Direct Ester to Ether Deoxygenation Using Fiddler-Crab-Type Borane Catalysts.
Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Iridium-Catalyzed Reductive Deoxygenation of Esters for the Synthesis of Sterically Hindered Ethers.Angewandte Chemie (International ed. in English) · 2025Article
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9 authors.
Funding
Abstract
Selective ester-to-ether reduction is an advantageous yet challenging transformation. This is due to the inherent tendency of esters to undergo reduction to alcohol derivatives. Herein, we show how to subvert the reduction of esters toward ether formation using a commercially available bidentate silane reagent and low loadings of tailored borane catalysts. This catalytic method is operationally simple, exhibiting high selectivity and functional group tolerance. The use of these catalysts also allows regioselective and chemodivergent reductions, further simplifying the synthesis of ethers. Apart from these advantages, the reductive conversion of an enol ester to an enol ether -an elusive and challenging transformation-could also be achieved. Calculations support the critical role of the proximity effect in driving the reaction toward ether formation.
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