SynthesisFrontiers in public health2026
Age-related differences in the effectiveness of neuromuscular training for preventing anterior cruciate ligament injuries in athletes: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Age-moderating effects and training characteristics of neuromuscular training for preventing knee injuries: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Anterior cruciate ligament (ACL) injuries are common in competitive sports and may lead to long-term functional impairment and substantial career burden. Neuromuscular training (NMT) has been proposed to reduce the risk of ACL injury; however, whether its preventive effectiveness differs by age remains controversial. This systematic review and meta-analysis quantitatively evaluated the protective effects of NMT across different age groups. Methods: Five databases were systematically searched for studies evaluating the effect of NMT on the incidence of ACL injury. Pooled effects were synthesized using random-effects models and reported as odds ratios (ORs) with 95% confidence intervals (CIs). Age-stratified subgroup analyses and meta-regression (using the study-level mean age as a continuous moderator) were conducted to explore potential age-related differences in effectiveness. Results: A total of 19 studies met the inclusion criteria and contributed to the primary meta-analysis. The random-effects meta-analysis showed that NMT significantly reduced ACL injury risk (OR = 0.456, 95% CI: 0.331-0.627, Conclusion: NMT significantly reduces the risk of ACL injury in athletes. Current evidence suggests that its protective effect may be greater in younger athletes and may attenuate with increasing age. As the available evidence is derived predominantly from female cohorts, further research is needed to clarify whether a similar age-related pattern exists in male athletes. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251218902, identifier: CRD420251218902.
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