SynthesisFrontiers in oral health2026
Clinical outcomes, complications and impact on quality of life following orthognathic surgery: a systematic review.
Synthesis in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Cross-Cultural Adaptation and Validation of the Polish Version of the Orthognathic Quality of Life Questionnaire (OQLQ).Journal of clinical medicine · 2026Article
- Latent profiles and associated factors of readiness for hospital discharge among patients undergoing orthognathic surgery: a cross-sectional study.Frontiers in public health · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Orthognathic surgery is a definitive treatment for dentofacial deformities, yet comprehensive synthesis of clinical outcomes, complications, and quality of life impacts remains limited. This systematic review critically evaluates contemporary evidence on orthognathic surgery effectiveness and safety. Methods: A systematic search of PubMed/MEDLINE, Embase, Cochrane CENTRAL, Web of Science, and Scopus was conducted through December 2024. Studies reporting clinical outcomes, complications, or quality of life following orthognathic surgery in patients with dentofacial deformities were included. Quality assessment employed the Cochrane Risk of Bias tool and Newcastle-Ottawa Scale. Meta-analysis with random-effects models was performed where appropriate. Results: Sixty-five studies encompassing 6,482 patients were included. Mean ANB angle improvements were 6.8° (95% CI: 6.2-7.4°) for class III and 5.4° (95% CI: 4.9-5.9°) for class II corrections, with 87.3% maintaining skeletal stability at ≥1-year follow-up. Overall complication rate was 32.4% (95% CI: 28.7-36.1%), predominantly minor and self-limiting. Neurosensory disturbances occurred in 52.8% of cases, with 92.6% recovering by 12 months and permanent alterations in 3.4%. Relapse (>2mm) occurred in 18.7% of cases. Quality of life demonstrated substantial improvements with standardized mean difference of -1.84 (95% CI: -2.12 to -1.56, p < 0.001) for OQLQ total scores. Patient satisfaction reached 87.6% (95% CI: 84.2-91.0%), with higher ratings for aesthetic vs. functional outcomes.Conclusion: Orthognathic surgery effectively corrects dentofacial deformities with significant clinical and quality of life improvements. However, moderate complication rates and relapse risk necessitate careful patient selection, informed consent, and long-term follow-up.Keywords: orthognathic surgery; dentofacial deformities; systematic review; quality of life; complications; patient satisfaction; skeletal stability; neurosensory disturbances.
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