ArticleCirculation reports2026
Impact of Heart Disease and Multimorbidity on Oral Frailty in Japanese Community-Dwelling Older Adults.
Article in Circulation reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Oral frailty (OF), defined as a multidimensional decline in oral function, is an early marker of functional vulnerability in older adults. Although frailty is linked to cardiovascular disease incidence and prognosis, the relationship between OF, heart disease (HD), and multimorbidity (MM) remains unclear. Methods and Results: We conducted a cross-sectional analysis of 16,294 community-dwelling adults aged ≥65 years in the 2022 Japan Gerontological Evaluation Study. OF was assessed using the Oral Frailty 5-item Checklist. Among 1,575 participants with HD, we compared those with HD alone and those with HD plus comorbidities (HD+MM). We also compared OF and its components across the 4 groups based on HD and MM status. The overall prevalence of OF was 33.9%, increasing to 42.9% in individuals with HD. OF was significantly more prevalent in the HD+MM group than in the HD-only group (44.3% vs. 36.2%). Respiratory, digestive, immune, and ear diseases were strongly associated with OF. Furthermore, OF, lower Tokyo Metropolitan Institute of Gerontology Index of Competence scores, and higher body mass index were independently associated with a greater comorbidity burden in older adults. Conclusions: OF is common in older adults with HD, particularly in those with MM. Incorporating oral function assessment into cardiovascular risk evaluation may help identify high-risk individuals and support comprehensive management strategies for the aging population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.