ArticleWorld journal of gastrointestinal pharmacology and therapeutics2026
Right biopsy protocol for microscopic colitis: Reduced workload and carbon footprint while maintaining diagnostic accuracy.
Article in World journal of gastrointestinal pharmacology and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Letter to the Editor: Less can be more, rethinking colonic biopsy strategies for microscopic colitis in the era of green endoscopy.World journal of gastrointestinal pharmacology and therapeutics · 2026Article
- Resource Optimization in the Examination of Macroscopic Normal Colon Mucosa.Endoscopy international open · 2026Article
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13 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHistological findings of microscopic colitis (MC) are patchy, with potential for missed diagnoses. While guidelines recommend biopsies from the right and left sides of the colon, the optimal approach remains uncertain.
aimTo interrogate diagnostic biopsies in a cohort of patients with confirmed MC with a view to improving biopsy protocols.
methodsWe conducted a retrospective study of index colonoscopies in patients with MC over a 14-year period. We recorded demographics, symptoms, total number and location of biopsies, and whether they revealed features of lymphocytic or collagenous colitis.
resultsA total of 228 index colonoscopies were included: 64% (145/228) lymphocytic colitis and 36% (83/228) collagenous colitis. The median age at diagnosis was 60 (interquartile range: 48-72) years, with 27% (61/228) aged < 50 years. Overall, 71% (162/228) of the patients were female, similar across subtypes. Males were older at diagnosis than females (62
conclusionIn the era of green endoscopy, our data support a protocol of taking biopsies from at least two sites in the right colon only, processed in a single container.
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