Evidence map›Paper›PMID 42273239›Full record

ArticleWorld journal of gastrointestinal pharmacology and therapeutics2026

Effect of cholecystectomy on liver fat and fibrosis in metabolic dysfunction-associated steatotic liver disease patients.

Khellaf Amalou, Nassila Belal, Abdelghani Tibouk, Yasmine Ghedada, Rym Rekab, Sabrina Fadel, Nabil Debzi, Abderezak Bousloub

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In one paragraph

Article in World journal of gastrointestinal pharmacology and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khellaf AmalouDepartment of Gastroenterology, Mohamed Seghir Nekkache, Algiers 16000, Algeria. amalou_kh@yahoo.fr.
Nassila BelalDepartment of Radiology, Mohamed Seghir Nekkache, Algiers 16000, Algeria.
Abdelghani TiboukDepartment of Pathology, Mohamed Seghir Nekkache, Algiers 16000, Algeria.
Yasmine GhedadaDepartment of Biology, Mohamed Seghir Nekkache, Algiers 16000, Algeria.
Rym RekabDepartment of Gastroenterology, Mohamed Seghir Nekkache, Algiers 16000, Algeria.
Sabrina FadelDepartment of Gastroenterology, Mohamed Seghir Nekkache, Algiers 16000, Algeria.
Nabil DebziDepartment of Gastroenterology, CHU Mustafa, Algiers 16000, Algeria.
Abderezak BousloubDepartment of Gastroenterology, Mohamed Seghir Nekkache, Algiers 16000, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent worldwide. Experimental studies have shown that cholecystectomy (Chx) increases metabolic dysfunction-associated steatotic liver (MASL) and is associated with MASLD in large retrospective cohort studies.

aimTo prospectively evaluate the effect of Chx on MASL and fibrosis, assess the prevalence of MASLD, and identify its risk factors in this population.

methodsThere were 213 MASLD patients enrolled, with 103 being Chx and 110 being non-Chx patients. The patients were followed up for 36 months.

resultsBody mass index increased in the Chx group (30.15 ± 4.08 to 31.58 ± 4.64)

conclusionChx increases MASL and fibrosis. MASLD prevalence in the Chx group is higher than in the overall population.

Indexed as

CholecystectomyHepatic fibrosisMetabolic dysfunction-associated steatohepatitisMetabolic dysfunction-associated steatotic liverMetabolic dysfunction-associated steatotic liver disease

Identifiers

PMID42273239
PMCPMC13248080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.