Evidence map›Paper›PMID 42273236›Full record

ArticleCase reports in critical care2026

Macroscopic Pulmonary Fat Embolism Secondary to Intraosseous Line Placement: A Case Report.

Stephanie J Chen, Andrew C Sanchez, Serena T Hua, Joel N Murala, Charisma J Kaushik, Amit Banga, Gundeep S Dhillon

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Article in Case reports in critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie J ChenDivision of Pulmonary, Allergy and Critical Care Medicine, Stanford University, Stanford, California, USA, stanford.edu.ORCID https://orcid.org/0009-0008-3850-6222
Andrew C SanchezDepartment of Pathology, Stanford University, Stanford, California, USA, stanford.edu.ORCID https://orcid.org/0009-0001-7778-0258
Serena T HuaDivison of Emergency Medicine, The Permanente Medical Group, Inc., Oakland, California, USA, kaiserpermanente.org.ORCID https://orcid.org/0009-0002-3390-9600
Joel N MuralaDepartment of Pharmacology and Physiology, Georgetown University, Washington DC, USA, georgetown.edu.ORCID https://orcid.org/0009-0006-2872-8310
Charisma J KaushikDepartment of Critical Care Medicine, Stanford University, Stanford, California, USA, stanford.edu.ORCID https://orcid.org/0009-0008-6926-457X
Amit BangaDivision of Pulmonary, Allergy and Critical Care Medicine, Stanford University, Stanford, California, USA, stanford.edu.ORCID https://orcid.org/0000-0002-6932-1537
Gundeep S DhillonDivision of Pulmonary, Allergy and Critical Care Medicine, Stanford University, Stanford, California, USA, stanford.edu.ORCID https://orcid.org/0000-0003-0440-1138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intraosseous access is commonly used for vascular access in emergent settings. It is generally thought to be well tolerated with minimal complications. We report the first case of clinically significant macroscopic pulmonary fat embolism secondary to intraosseous access. Case Presentation: A 67-year-old woman developed profound hypotension and severe biventricular dysfunction shortly after intraosseous access and resuscitation. She required emergent venoarterial extracorporeal membrane oxygenation and Impella for cardiopulmonary support. Computed tomography revealed a new macroscopic pulmonary fat embolism compared with prior imaging 1 day prior. Aspiration thrombectomy was successfully performed with significant improvement in hemodynamics. Unfortunately, she suffered an anoxic brain injury during resuscitation and was ultimately transitioned to comfort care. Conclusions: Although intraosseous access is often considered a safe procedure, this case highlights the need for awareness of this rare but serious and potentially lethal complication. Treatment of pulmonary fat embolism is often supportive; however, aspiration thrombectomy has a potential therapeutic role in macroscopic cases.

Identifiers

PMID42273236
PMCPMC13247423

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.