Evidence map›Paper›PMID 42273147›Full record

ArticleQuantitative imaging in medicine and surgery2026

Synthetic and conventional magnetic resonance imaging for knee assessment in children with leukemia: a comparative study.

Wenfeng Jin, Hongding Zhang, Yi Liao, Shiyu Xiong, Xiangao Lei, Xia Guo, Zhigang Yang, Ruzhi Zhang, Huilou Liang, Yingkun Guo and 4 more

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In one paragraph

Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wenfeng Jin *Department of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Hongding Zhang *Department of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Yi LiaoDepartment of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Shiyu XiongDepartment of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Xiangao LeiDepartment of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Xia GuoDepartment of hematology, West China Second University Hospital, Sichuan University, Chengdu, China.
Zhigang YangDepartment of Radiology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Ruzhi ZhangGE Healthcare China, Beijing, China.
Huilou LiangGE Healthcare China, Beijing, China.
Yingkun GuoDepartment of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Qing WuAffiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, China.
Lu YeDepartment of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Jieqian Zheng *Department of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.
Rong Xu *Department of Radiology, Medical Imaging Center, West China Second University Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Magnetic resonance imaging (MRI) is an ideal method for the detection of osteonecrosis in children with acute lymphoblastic leukemia (ALL), but some children struggle to adhere to the procedure due to its lengthy examination time. This study evaluated the feasibility of synthetic MRI for knee examinations in children with ALL. Methods: This prospective study included 33 children with ALL who underwent conventional and synthetic MRI. Participants were categorized into Group A (>8 years, n=23) and Group B (≤8 years, n=10). Scan time, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), motion artifacts, image quality score, lesion detection, and T2 values were compared using paired Results: Synthetic MRI significantly reduced scan time (Group A: 286±74 Conclusions: For pediatric leukemia patients capable of maintaining stillness, synthetic MRI shortens acquisition time while preserving diagnostic accuracy and quantitative precision. However, due to motion susceptibility, its clinical use should be limited to cooperative children.

Indexed as

Acute lymphoblastic leukemia (ALL)kneemagnetic resonance imaging (MRI)synthetic imagingT2 mapping

Identifiers

PMID42273147
PMCPMC13247900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.