ArticleQuantitative imaging in medicine and surgery2026
Multimodal ultrasound for precise quantitative evaluation of diaphragmatic lesions in idiopathic inflammatory myopathy: a promising assessment tool.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Idiopathic inflammatory myopathy (IIM) is a systemic autoimmune disorder in which respiratory failure, driven by diaphragmatic dysfunction and interstitial lung disease (ILD), is a leading cause of mortality. This study aimed to evaluate IIM-related diaphragmatic involvement via multimodal ultrasound, integrating high-frequency ultrasound (HFUS), M-mode imaging, and ultrasound viscoelasticity imaging (UVI). Methods: In this study, 93 IIM patients and 51 matched healthy controls (HCs) underwent diaphragmatic multimodal ultrasound assessments, including measurements of thickness, excursion, and viscoelastic properties [shear wave speed (Cs), viscosity index (Vi), and dispersion slope (Disp)]. Multivariate logistic regression and receiver operating characteristic (ROC) curve analyses were conducted to identify independent predictors of IIM and to assess the diagnostic efficacy of distinguishing IIM patients from HCs. Subgroup ROC analysis was performed within the IIM cohort to evaluate parameters for identifying respiratory involvement. Additionally, correlations between ultrasound parameters and clinical indicators (serological markers, antibodies, and ILD status) were analyzed. In total, 17 IIM patients completed post-treatment follow-up ultrasound examinations. Results: Compared with the HCs, the patients with IIM exhibited a significantly reduced diaphragmatic thickening fraction (DTF) (HC group: 111.8% Conclusions: Multimodal ultrasound enables the early detection and quantitative monitoring of diaphragmatic impairment in IIM. Viscoelastic parameters, particularly the Vi, may aid in the identification of patients with respiratory involvement. Diaphragmatic functional parameters (excursion and the DTF) are responsive to treatment and may serve as objective biomarkers for monitoring the therapeutic response, complementing conventional serological assessments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.