ArticleQuantitative imaging in medicine and surgery2026
Parameter response mapping does not enhance the correlations of conventional CT quantitative metrics with lung function and subjective symptoms in chronic obstructive pulmonary disease.
Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Parameter response mapping (PRM) has been employed in chronic obstructive pulmonary disease (COPD) assessments, providing a more accurate characterization of emphysema and air trapping. This study aimed to evaluate and compare the correlations of PRM and conventional computed tomography (CT) quantitative metrics with lung function and subjective symptoms in COPD patients. Methods: A total of 94 COPD patients were prospectively enrolled who underwent inspiratory and expiratory dual-phase CT scans and pulmonary function tests (PFTs) at The Second People's Hospital of Quzhou from January 2023 to June 2024. PRM parameters (emphysema area, PRM Results: Both PRM and conventional CT quantitative parameters correlated with PFT outcomes. Notably, strong correlations were observed for both FEV Conclusions: PRM metrics demonstrated strong correlations with pulmonary function and patients' subjective symptom scores, particularly PRM
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