Evidence map›Paper›PMID 42273030›Full record

SynthesisFrontiers in neurology

Electroencephalography for monitoring cortical electrical activity related to intracranial pressure in patients with traumatic brain injury: a systematic review.

Jelmer-Joost Lenstra, Gustavo E Marcolin, Bram Jacobs, Ulf Günther, Jan-Willem Elting, Gea Drost, Michel J A M van Putten, Joukje van der Naalt, Harm J van der Horn

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jelmer-Joost LenstraDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Gustavo E MarcolinDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Bram JacobsDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Ulf GüntherDepartment of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Jan-Willem EltingDepartment of Clinical Neurophysiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Gea DrostDepartment of Clinical Neurophysiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Michel J A M van PuttenDepartment of Clinical Neurophysiology, Medisch Spectrum Twente, University of Twente, Twente, Netherlands.
Joukje van der NaaltDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Harm J van der HornDepartment of Neurology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial pressure (ICP) driven treatment of patients with traumatic brain injury (TBI) in the Intensive Care Unit (ICU) remains a continuous challenge. Patients are sedated and therapy focuses on preventing secondary injury caused by an increase in ICP and reduction of cerebral blood flow (CBF). While ICP-monitoring provides valuable information on secondary deterioration, it offers limited insight into the complex and dynamic intracranial processes following TBI and carries the risk of complications (hemorrhage, infections). Integration of noninvasive advanced monitoring modalities to understand this process is mandatory. Electroencephalography (EEG) monitoring provides an advanced noninvasive method to measure focal cerebral electrical activity in real-time and is particularly sensitive to cortical oxygen and metabolic deficits. Investigations of the relationship between disruptions in EEG patterns and traditional invasive ICP measurements could provide valuable insights into the pathophysiology of intracranial hypertension and may pave the way for using continuous EEG in future ICP management. To date, no systematic review has evaluated the relationship between EEG and ICP in adult patients with TBI. This systematic review was conducted according to the PRISMA-guidelines. Three studies specifically reported on the incidence of post-traumatic seizures and ICP, and one study reported on a directional relationship between EEG activity and ICP. Altogether, there is a paucity of evidence and studies investigating the relationship between EEG and ICP. This highlights the need for systematic, well-powered research to clarify their interplay and underlying pathophysiology.

Indexed as

electroencephalographyintracranial pressuremultimodal monitoringsystematic reviewtraumatic brain injury

Identifiers

PMID42273030
PMCPMC13246425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.