Evidence map›Paper›PMID 42272977›Full record

ArticleBioengineering & translational medicine2026

A multifactorial intervertebral disc degeneration model: Integrating inflammation, structural disruption, biomechanical parameters, and neural sensitization.

Marcia Muerner, Junxuan Ma, Rathina V Balasubramanian, Chencheng Feng, Julia Fernández Pérez, Aleksandr Ovsianikov, Sibylle Grad

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcia MuernerAO Research Institute Davos Davos Switzerland.ORCID https://orcid.org/0009-0006-5305-2113
Junxuan MaAO Research Institute Davos Davos Switzerland.ORCID https://orcid.org/0000-0001-8923-9832
Rathina V BalasubramanianResearch Group 3D Printing and Biofabrication Technische Universität Wien Vienna Austria.ORCID https://orcid.org/0000-0003-0295-1718
Chencheng FengAO Research Institute Davos Davos Switzerland.ORCID https://orcid.org/0000-0002-9393-304X
Julia Fernández PérezResearch Group 3D Printing and Biofabrication Technische Universität Wien Vienna Austria.ORCID https://orcid.org/0000-0002-8375-2907
Aleksandr OvsianikovResearch Group 3D Printing and Biofabrication Technische Universität Wien Vienna Austria.ORCID https://orcid.org/0000-0001-5846-0198
Sibylle GradAO Research Institute Davos Davos Switzerland.ORCID https://orcid.org/0000-0001-9552-3653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intervertebral disc (IVD) degeneration (IVDD) is a major cause of low back pain, yet treatment options remain limited. Robust IVDD models are essential for discovering and validating new regenerative treatments.

Indexed as

animalbioreactorsdisease modelsintervertebral discintervertebral disc degenerationlow Back painorgan culture techniques

Identifiers

PMID42272977
PMCPMC13247399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.