ArticleBiomaterials research2026
Click Chemistry Mediated Immune Synapse Augmentation in Natural Killer Cell-Cancer Membrane Engagement and Facilitated Anticancer Efficacies of Natural Killer Cell Therapy.
Article in Biomaterials research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-small cell lung cancer remains a major clinical challenge due to aggressive metastasis and limited therapeutic modalities. The innate cytotoxicity of natural killer (NK) cells and their ability to eliminate malignant cells in an antigen-independent manner have attracted considerable interest for cancer immunotherapy. However, the therapeutic performance of NK cells in solid tumors is severely constrained by (a) tumor heterogeneity, (b) physical barriers within the tumor microenvironment, and (c) insufficient tumor-targeting specificity. To address these challenges, we here develop a lipid biomaterial that enables the simultaneous surface engineering of cancer and NK cells to enhance their physical engagement within complex tumor microenvironments. The developed lipid biomaterials are composed of (a) a lipid moiety for stable surface anchoring and (2) complementary dibenzocyclooctyne (DBCO) and azide (N
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.