Evidence map›Paper›PMID 42272918›Full record

ArticleBiomarkers in neuropsychiatry2025

Associations of social and genetic background variables to neuro-cognitive biomarkers of psychosis.

Parker V Jarrett, Kiernan L O'Mara, Audrey L Berardi, Kelsey E Roberts, John T Greco, Rebekah L Trotti, David A Parker, Sarah K Keedy, Godfrey D Pearlson, Matcheri S Keshavan and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomarkers in neuropsychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Parker V JarrettDepartment of Psychology, University of Georgia, Athens, GA, USA.ORCID 0009-0002-1689-3598
Kiernan L O'MaraDepartment of Psychology, University of Georgia, Athens, GA, USA.ORCID 0009-0005-6469-1095
Audrey L BerardiDepartment of Psychology, University of Georgia, Athens, GA, USA.ORCID 0009-0004-7811-3109
Kelsey E RobertsDepartment of Psychology, University of Georgia, Athens, GA, USA.
John T GrecoDepartment of Psychology, University of Georgia, Athens, GA, USA.
Rebekah L TrottiDepartment of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4660-5219
David A ParkerDepartment of Psychology, University of Georgia, Athens, GA, USA.
Sarah K KeedyDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.
Godfrey D PearlsonDepartments of Psychiatry and Neuroscience, Yale University, School of Medicine, New Haven, CT, USA.
Matcheri S KeshavanDepartment of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
S Kristian HillDepartment of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Elena I IvlevaDepartment of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA.
Carol A TammingaDepartment of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA.
Jennifer E McDowellDepartment of Psychology, University of Georgia, Athens, GA, USA.
Ezra SusserMailman School of Public Health, Columbia University, New York, NY, USA.
Brett A ClementzDepartment of Psychology, University of Georgia, Athens, GA, USA.

Funding

Bipolar & Schizophrenia Consortium for Parsing Intermediate PhenotypesR01MH077851 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI TAMMINGA, CAROL A · 2007 to 2019
$7.8M
Bipolar & Schizophrenia Consortium for Parsing Intermediate PhenotypesR01MH077945 · NIMH · YALE UNIVERSITY · PI PEARLSON, GODFREY D · 2007 to 2019
$7.6M
Stability of Biotypes: a Longitudinal EvaluationR01MH078113 · NIMH · WAYNE STATE UNIVERSITY · PI KESHAVAN, MATCHERI S. · 2007 to 2019
$6.2M
Stability of Biotypes: a Longitudinal Evaluation (STABLE)R01MH103368 · NIMH · UNIVERSITY OF CHICAGO · PI GERSHON, ELLIOT S, KEEDY, SARAH K · 2015 to 2019
$4.5M
5/5 BIPOLAR-SCHIZOPHRENIA NETWORK FOR INTERMEDIATE PHENOTYPES (B-SNIP) - Resubmission - 1R01MH103366 · NIMH · UNIVERSITY OF GEORGIA · PI CLEMENTZ, BRETT A, GIBBONS, ROBERT D · 2015 to 2019
$3.8M
Bipolar & Schizophrenia Consortium for Parsing Intermediate PhenotypesR01MH077862 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI SWEENEY, JOHN A · 2007 to 2010
$3.1M
NIMH NIH HHS R01 MH077851NIMH NIH HHS R01 MH077862NIMH NIH HHS R01 MH077945NIMH NIH HHS R01 MH078113NIMH NIH HHS R01 MH103366NIMH NIH HHS R01 MH103368
6 · The paper itself

Abstract

Socioeconomic (SES) and ethno-racial factors may tilt psychosis diagnoses for persons from different backgrounds. Clinical diagnoses depend on patient and informant reports and are suspected of being susceptible to unintended bias. Diagnoses using laboratory tests are thought to be objective. Social disadvantages, however, alter brain functions related to psychosis. Race and class bias in laboratory medical diagnostics is an area of concern. To probe these issues for psychosis diagnoses, we describe relationships of SES, race/ethnicity, and ancestral genetic background to 11 integrated laboratory bio-factors that are associated with DSM categories and distinguish B-SNIP Biotypes. A series of analyses evaluated relationships of social factors and ancestry-related genetic background to those bio-factors: (i) canonical correlation revealed that SES and race (a social construct) are strongly associated (r

Identifiers

PMID42272918
PMCPMC13249451

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.