SynthesisFrontiers in nutrition2026
Global research trends and mechanistic pathways linking micro- and nano plastics exposure to metabolic health: a bibliometric and evidence-mapping analysis (2013-2025).
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The widespread presence of micro- and nanoplastics (MNPs) in the food chain has raised concerns regarding their potential contribution to metabolic diseases. Objective: However, a comprehensive synthesis of the intellectual structure, thematic evolution, and biomarker evidence linking dietary MNP exposure to metabolic health outcomes remains limited. Methods: This study conducted a bibliometric analysis of publications indexed in Scopus and Web of Science Core Collection (WoS) between 2013 and 2025. Bibliometrix/Biblioshiny and VOSviewer were applied for performance analysis, science mapping (co-occurrence, co-citation, bibliographic coupling), thematic evolution, and biomarker-domain mining. A biomarker-mechanism evidence matrix was developed to integrate mechanistic insights. Results: 1,613 entries were found in WoS out of the 1,725 papers in the Scopus dataset, indicating consistent publication trends across databases. After 2019, there was a significant increase in annual research production, which was indicative of the expanding interdisciplinary attention to metabolic concerns linked with MNP. The publication landscape is dominated by environmental toxicology journals, which are increasingly contributing worldwide and have a large geographic concentration in China. Four important research areas were found by keyword co-occurrence analysis: mammalian metabolic toxicity, gut microbiota dysbiosis, aquatic ecotoxicology, and developing human health risk assessment. Oxidative stress and exposure pathways were identified as major themes by thematic mapping, while gut microbiota-metabolic interactions represent quickly developing research avenues. Conclusion: Human epidemiological evidence remains limited compared to animal mechanistic studies, highlighting gaps in realistic exposure assessment and standardized cardiometabolic biomonitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.