ArticleFrontiers in pediatrics2026
Partly intraoperative cell salvage in pediatric craniocerebral trauma: effects on coagulation function, allogeneic blood requirements, and clinical outcomes - a propensity score-matched retrospective cohort study.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Traumatic brain injury (TBI) in children frequently necessitates intraoperative blood transfusion owing to the hemorrhagic risk associated with hematoma evacuation. Intraoperative cell salvage (ICS) offers a strategy to reduce allogeneic blood exposure. However, the impact of partial usage of ICS on coagulation function in the pediatric neurosurgical setting remains insufficiently characterized. Methods: This retrospective cohort study enrolled 136 children (aged 1-18 years) who underwent cerebral hematoma evacuation between February 2016 and April 2022. Patients receiving combined autologous and allogeneic transfusion constituted the ICS group ( Results: Following PSM, allogeneic blood consumption was significantly higher in the ABL group (P < 0.001), while total red cell volume did not differ. No significant intergroup differences were detected in postoperative PT, APTT, INR, PLT, Hb, Hct, or serum electrolytes (all Conclusion: Partial intraoperative autologous blood salvage in pediatric hematoma evacuation reduces allogeneic blood consumption and the incidence of postoperative coagulation disorders without impairing standard coagulation indices or electrolyte balance. These findings are hypothesis-generating and require confirmation in prospective multicenter trials.
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