Evidence map›Paper›PMID 42272397›Full record

ArticleJournal of the International Association of Providers of AIDS Care

Determinants of Adoption, Implementation, Reach, and Sustainability of PrEP Services in a Sexual Health Clinic in Canada: A Qualitative Analysis Using CFIR and REAIM.

Emma Nagy, Beatriz Alvarado, Miriam Kamotho, Nicole Szumlanski, Tianxiu Hugh Guan, Jorge Martinez-Cajas

Abstract read
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emma NagyKnowledge Management, Southeast Public Health, Kingston, ON, Canada.ORCID 0000-0002-5161-3654
Beatriz AlvaradoDepartment of Public Health Sciences, Queen's University, Kingston, ON, Canada.ORCID 0000-0002-1269-405X
Miriam KamothoSexual Health Team, Southeast Public Health, Kingston, ON, Canada.
Nicole SzumlanskiSexual Health Team, Southeast Public Health, Kingston, ON, Canada.
Tianxiu Hugh GuanKnowledge Management, Southeast Public Health, Kingston, ON, Canada.
Jorge Martinez-CajasDivision of Infectious Diseases, Department of Medicine, Queen's University, Kingston, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundSexual health clinics are promising settings for HIV pre-exposure prophylaxis (PrEP), yet implementation in mixed urban-rural regions remains underexplored. This study evaluated the implementation of a PrEP clinic in a mid-sized Ontario region within a public health setting, including adoption, implementation model, reach, perceived effectiveness, and key determinants.MethodsGuided by RE-AIM and the Consolidated Framework for Implementation Research (CFIR), we conducted an evaluation using process-mapping and interviews with staff (n = 7) and clients (n = 5).ResultsAdoption and implementation were supported by strong leadership, organizational culture, provider knowledge, and perceptions of PrEP as effective and simple. The clinic demonstrated high fidelity, sustained service delivery, and meaningful client engagement. However, reach remained uneven, with the program primarily serving insured populations. Medication costs, poverty, stigma, and geographic barriers limited equitable access.ConclusionsSexual health clinics can sustainably deliver PrEP, but equitable scale-up requires structural reforms, diversified delivery models, and stronger community partnerships.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexual HealthFemaleHumansMaleOntarioCFIRHIV pre-exposure prophylaxisimplementation scienceRE-AIMsexual health clinics

Identifiers

PMID42272397
PMCPMC13260786

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.