ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2026
Short- and long-term outcomes of IPAA for ulcerative colitis in Latin America: A retrospective, multicentre assessment.
Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Further considerations on long-term outcomes following ileal pouch-anal anastomosis for ulcerative colitis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Short- and long-term outcomes of IPAA for ulcerative colitis in Latin America: A retrospective, multicentre assessment.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
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Abstract
introductionData on ileal pouch-anal anastomosis (IPAA) outcomes in ulcerative colitis (UC) patients from resource-constrained settings, such as Latin America, are limited. This study aimed to evaluate demographic characteristics, perioperative outcomes and long-term results of UC patients undergoing IPAA in Latin America.
methodsA retrospective analysis was conducted on UC patients who underwent IPAA at 11 academic centres across Argentina, Brazil, Chile and Colombia between 2012 and 2022. Main outcome was 30-day postoperative complications.
resultsA total of 273 patients underwent IPAA; 49.8% were female, with a mean age of 37.5 years. Three-stage IPAA was performed in 68.9% of cases, while 31.1% underwent a two-stage approach. A minimally invasive technique was used in 50% of cases, with a 4% conversion rate. The 30-day complication rate was 36.6%, and 30-day mortality was 0.7%. On multivariate analysis, use of advanced therapies within 12 weeks of surgery was protective against postoperative complications (OR 0.24, p = 0.008), whereas ASA III/IV status was independently associated with higher complication rates (OR 5.14, p = 0.043). Long-term follow-up was available for 176 patients (median 60 months). IPAA-related complications occurred in 31.5%, including pouchitis, strictures, cuffitis and fistula formation. Pouch failure was observed in 8.5%.
conclusionIPAA for UC in Latin America shows acceptable morbidity, low mortality and long-term outcomes comparable to high-resource settings, supporting its feasibility in resource-constrained environments.
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