ArticleJournal of cardiothoracic surgery2026
Development and validation of a predictive model for postoperative complications in thymoma patients.
Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Development and Temporal Validation of Staged Prediction Models for Acute Respiratory Distress Syndrome After Thymic Epithelial Tumour Resection.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo develop and validate an intervention model for the risk factors of postoperative complications in patients with thymoma.
methodsA retrospective analysis was conducted on the clinical data of patients who underwent thymoma resection surgery at our hospital between June 2006 and July 2024. Postoperative complications were systematically categorized according to the Clavien-Dindo classification (Grade II-V), including but not limited to: ① 30-day mortality, ② respiratory failure (defined as mechanical ventilation > 48 h or unplanned reintubation), ③ myocardial injury (troponin elevation > 5×ULN).Whether complications occurred was divided into two groups. The data were randomly divided into a modeling cohort (70%) and a validation cohort (30%). Logistic regression was used to identify risk factors for postoperative complications, and model performance was evaluated using ROC curves and calibration plots.
resultsA total of 26.1% (66/253) of thymoma patients developed postoperative complications. Multivariable logistic regression analysis revealed that Masaoka-Koga stage, Myasthenia Gravis, intraoperative blood loss, forced expiratory volume in 1 second, and albumin were significant predictors in the model. The model demonstrated an area under the ROC curve of 0.84 (95% CI: 0.78-0.91) in the modeling cohort and 0.76 (95% CI: 0.63-0.89) in the validation cohort. The Hosmer-Lemeshow goodness-of-fit test showed: modeling cohort (χ2 = 5.0997, P = 0.6478), validation cohort (χ2 = 4.9946, P = 0.7582). Decision curve analysis indicated that the risk thresholds for the modeling and validation cohorts were 10%-70% and 10%-60%.
conclusionThis study developed a risk prediction model for postoperative complications in thymoma patients, demonstrating strong discriminative ability (C-statistic 0.82, 95% CI 0.78-0.86) and calibration (Brier score 0.11) upon internal validation. The model may aid in identifying high-risk patients for targeted preventive measures, though its impact on actual complication rates requires prospective intervention trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.