Evidence map›Paper›PMID 42271051›Full record

ArticleNature2026

A prognostic human brain network for diffuse midline glioma.

Jai Sidpra, Valentina Lind, Alexander L Cohen, Frederic L W V J Schaper, Thomas J Stone, Yura Grabovska, Asthik Biswas, Sniya Sudhakar, Francisco Sepulveda, Bruno S Peres and 41 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. An MRI Atlas of Regional Brain Vulnerability to Metastatic Disease.medRxiv : the preprint server for health sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

51 authors.

Jai Sidpra *Developmental Biology and Cancer Section, University College London Great Ormond Street Institute of Child Health, London, UK. jai.sidpra@ucl.ac.uk.ORCID http://orcid.org/0000-0003-1985-5503
Valentina Lind *Developmental Biology and Cancer Section, University College London Great Ormond Street Institute of Child Health, London, UK. v.lind@ucl.ac.uk.ORCID http://orcid.org/0009-0002-4842-6038
Alexander L CohenCenter for Brain Circuit Therapeutics, Departments of Neurology, Psychiatry, Neurosurgery, and Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6557-5866
Frederic L W V J SchaperCenter for Brain Circuit Therapeutics, Departments of Neurology, Psychiatry, Neurosurgery, and Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-5487-0923
Thomas J StoneDevelopmental Biology and Cancer Section, University College London Great Ormond Street Institute of Child Health, London, UK.
Yura GrabovskaCentre for Children and Young People's Cancer, Division of Cancer Biology, Institute of Cancer Research, London, UK.ORCID http://orcid.org/0000-0003-3419-2234
Asthik BiswasDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Sniya SudhakarDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Francisco SepulvedaDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0003-1898-2869
Bruno S PeresDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Greta VeroneseUnit of Functional Neurosurgery, University College London Queen Square Institute of Neurology, London, UK.ORCID http://orcid.org/0009-0008-4955-1651
Cristina Alemán-CharletGenetics and Genomic Medicine Section, University College London Great Ormond Street Institute of Child Health, London, UK.
Olumide OgunbiyiDepartment of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Kiarash ShamardaniDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Jiaqi ZhaoDepartment of Neurology, Boston Children's Hospital, Boston, MA, USA.
Alberto Castro PalacinDepartment of Neurology, Boston Children's Hospital, Boston, MA, USA.
Gillian MillerDepartment of Neurology, Boston Children's Hospital, Boston, MA, USA.ORCID http://orcid.org/0009-0001-6306-8163
Raffaella S OpipariDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0003-4156-9001
Enrico De VitaDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0001-8068-1288
Deborah RidoutPopulation, Policy, and Practice Programme, University College London Great Ormond Street Institute of Child Health, London, UK.
Suely F FerraciolliNeuroradiology Section, Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, Brazil.
Leandro T LucatoNeuroradiology Section, Hospital das Clinicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, Brazil.
Jernej AvsenikClinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.ORCID http://orcid.org/0000-0003-4081-4140
Eleonora PiccirilliDepartment of Imaging, Oncological and Advanced Neuroradiology Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.ORCID http://orcid.org/0000-0003-3105-1292
Andrés Morales-La MadridNeuro-Oncology Unit, Paediatric Cancer Center, Sant Joan de Déu Barcelona Children's Hospital, University of Barcelona, Esplugues de Llobregat, Spain.
Jordi MuchartDepartment of Radiology, Sant Joan de Déu Barcelona Children's Hospital, University of Barcelona, Esplugues de Llobregat, Spain.ORCID http://orcid.org/0000-0003-4702-5072
Maura E RyanDepartment of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Rajan PatelDepartment of Pediatric Radiology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Parthiv HaldipurCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Ciaran S HillVictor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, London, UK.ORCID http://orcid.org/0000-0002-4488-4034
Marie T KrügerUnit of Functional Neurosurgery, University College London Queen Square Institute of Neurology, London, UK.
Ludvic ZrinzoUnit of Functional Neurosurgery, University College London Queen Square Institute of Neurology, London, UK.
Noor Ul Owase JeelaniDevelopmental Biology and Cancer Section, University College London Great Ormond Street Institute of Child Health, London, UK.
Juan Pedro Martinez-BarberaDevelopmental Biology and Cancer Section, University College London Great Ormond Street Institute of Child Health, London, UK.ORCID http://orcid.org/0000-0002-5292-7276
Andrew M DonsonMorgan Adams Foundation Pediatric Brain Tumour Research Program, Department of Pediatrics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Kathleen DorrisMorgan Adams Foundation Pediatric Brain Tumour Research Program, Department of Pediatrics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
Paul S MorganDepartment of Medical Physics and Clinical Engineering, Nottingham University Hospitals, Nottingham, UK.ORCID http://orcid.org/0000-0002-5870-1446
Alan MackayCentre for Children and Young People's Cancer, Division of Cancer Biology, Institute of Cancer Research, London, UK.
Humsa S VenkateshCenter for Brain Circuit Therapeutics, Departments of Neurology, Psychiatry, Neurosurgery, and Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-1194-3015
Andreas HornCenter for Brain Circuit Therapeutics, Departments of Neurology, Psychiatry, Neurosurgery, and Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-0695-6025
Sabine MuellerDepartment of Neurology, Neurosurgery and Pediatrics, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-8216-9357
Adam L GreenMorgan Adams Foundation Pediatric Brain Tumour Research Program, Department of Pediatrics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.
David M MirskyDepartment of Neuroradiology, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA.
Harith AkramUnit of Functional Neurosurgery, University College London Queen Square Institute of Neurology, London, UK.
Chris JonesCentre for Children and Young People's Cancer, Division of Cancer Biology, Institute of Cancer Research, London, UK.
Kristian AquilinaDepartment of Neurosurgery, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0001-7015-5196
Kshitij MankadDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Michelle MonjeDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-3547-237X
Thomas S JacquesDevelopmental Biology and Cancer Section, University College London Great Ormond Street Institute of Child Health, London, UK.ORCID http://orcid.org/0000-0002-7833-2158
Michael D FoxCenter for Brain Circuit Therapeutics, Departments of Neurology, Psychiatry, Neurosurgery, and Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Darren R HargraveDevelopmental Biology and Cancer Section, University College London Great Ormond Street Institute of Child Health, London, UK. d.hargrave@ucl.ac.uk.ORCID http://orcid.org/0000-0001-8219-9807

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system

Indexed as

BrainBrain NeoplasmsGliomaNerve NetChildChild, PreschoolFemaleHumansInfantMalePonsPrognosisSynapsesThalamus

Identifiers

PMID42271051
PMCPMC13372695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.