Evidence map›Paper›PMID 42271049›Full record

ArticleNature2026

Lignin to adipic acid in a high-yield chemical and biological redox process.

Kathryn M Mains, Chad T Palumbo, Davide Rigo, Matthew S Webber, Gloria Rosetto, Si Tong Bao, Austin L Carroll, Nicolette R Meyer, Alexander F Benson, Brett A Boyle and 13 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Kathryn M Mains *Renewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Chad T Palumbo *Renewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Davide Rigo *Renewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Matthew S Webber *Renewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Gloria RosettoRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.ORCID http://orcid.org/0009-0009-7116-7258
Si Tong BaoRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Austin L CarrollCenter for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID http://orcid.org/0009-0000-3468-6299
Nicolette R MeyerRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Alexander F BensonRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Brett A BoyleRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Stefan J HaugenRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Morgan A IngrahamRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
William G AlexanderCenter for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID http://orcid.org/0000-0003-4212-6392
Miriam SilbermanBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID http://orcid.org/0000-0003-2013-5968
Logan C MyersRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.ORCID http://orcid.org/0009-0002-5311-3108
Kelsey J RamirezRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Kevin P SullivanRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.ORCID http://orcid.org/0000-0003-3324-1145
Adam M GussCenter for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID http://orcid.org/0000-0001-5823-5329
Davinia SalvachúaRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA.
Yuriy Román-LeshkovDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-0025-4233
Shannon S StahlDepartment of Chemistry and Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA. stahl@chem.wisc.edu.ORCID http://orcid.org/0000-0002-9000-7665
Allison Z WernerRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA. allison.werner@nlr.gov.ORCID http://orcid.org/0000-0001-7147-2863
Gregg T BeckhamRenewable Resources and Enabling Sciences Center, National Laboratory of the Rockies, Golden, CO, USA. gregg.beckham@nlr.gov.ORCID http://orcid.org/0000-0002-3480-212X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viable manufacturing pathways to produce bio-based chemicals from renewable feedstocks, such as lignin derived from plant biomass, are needed to decarbonize the chemicals manufacturing sector. Converting the recalcitrant lignin polymer to valuable bioproducts remains a longstanding challenge in biorefining, with the highest reported single-product yield from lignin currently around 20 wt% (refs.

Indexed as

AdipatesLigninPseudomonas putidaBenzoic AcidCatalysisOxidation-ReductionPhthalic AcidsPopulusAdipatesadipic acidBenzoic AcidLigninPhthalic Acids

Identifiers

PMID42271049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.