ArticleCVIR endovascular2026
Emergency carotid artery stenting during endovascular treatment of tandem lesions in acute ischemic stroke: a single-center retrospective study.
Article in CVIR endovascular, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute ischemic stroke (AIS) can be caused by multiple factors, including intracranial large vessel occlusion (LVO), severe stenosis or occlusion of the cervical carotid artery, or both (tandem lesion). The optimal treatment strategy for tandem lesions remains unclear. This single-arm retrospective study aims to measure outcomes for tandem lesion patients who were treated with emergency carotid artery stenting (eCAS) during endovascular treatment (EVT). MATERIALS AND
methodsPatients who underwent EVT including eCAS for AIS with tandem lesions during the period 2015-2023 at our community teaching hospital in Western Europe were analyzed. Primary outcome was modified Rankin Scale (mRS) at 90-day follow up. Secondary outcomes were mortality within 30 days after stroke, symptomatic intracranial bleeding within 30 days after the stroke, major complications, and angiographic scores.
resultsOf the 600 patients who were treated with EVT, 64 underwent 65 eCAS procedures. Preprocedural National Institutes of Health Stroke Scale (NIHSS) scores of these 64 patients ranged from 2 to 24 (median 13). Expanded treatment in cerebral infarction (eTICI) scores immediately postprocedural were 0 (n = 1, 1.5%), 2a (n = 6, 9.2%), 2b (n = 31, 47.7%), 2c (n = 6, 9.2%), or 3 (n = 20, 30.8%). In 10.8% (n = 7) of eCAS procedures, complications occurred during the procedure and in 18.5% (n = 12) complications occurred during the follow-up period. In 9.2% (n = 6) of procedures, patients experienced symptomatic intracranial bleeding. Intracranial bleeding was observed more frequently in patients with preprocedural internal carotid artery (ICA) occlusion than stenosis but the difference was not statistically significant. At 90 days follow-up, in 41.5% (n = 27) of eCAS procedures, patients had an mRS score of ≤ 2. Binary logistic regression analysis revealed age and IV thrombolysis as significant predictors for death and age and a pretreatment low NIHSS score for a good functional outcome after 90 days (mRS 0-2). For bleeding complications none of the predictors reached statistical significance.
conclusionsEmergency carotid artery stenting during EVT for tandem lesions appears feasible with acceptable functional outcomes, despite the occurrence of symptomatic intracranial bleeding in 9% of patients. We must however await the results of randomized controlled trials before firm conclusions about the safety of eCAS can be drawn.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.