Trial reportObesity surgery2026
Five-year Outcomes After Single-Anastomosis Duodeno-Ileal Bypass (SADI) vs. Biliopancreatic Diversion with Duodenal Switch (BPD/DS): A Randomized Clinical Trial.
Trial report in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03938571 (Torsby I Trial), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Torsby I Trial: A Prospectively Randomized Study on Standard Duodenal Switch vs. Single Anastomosis Duodeno-ileostomy Duodenal Switch
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundSingle-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI) was introduced as a simplified modification of biliopancreatic diversion with duodenal switch (BPD/DS), aiming to maintain metabolic efficacy while shortening operating time and minimizing complications, including long-term nutritional deficiencies.
methodsThis single-center randomized trial enrolled adults with a body mass index > 45 kg/m² to either SADI or BPD/DS. The primary efficacy endpoint was 5-year percentage total weight loss (%TWL), and the primary safety endpoint was time to first unplanned reoperation within 5 years. Analyses were conducted in the treated population (n = 56; SADI n = 29, BPD/DS n = 27). The protocol was approved by the Regional Ethics Committee (Uppsala, Sweden) and registered at ClinicalTrials.gov (NCT03938571).
resultsFive-year weight data were available for 47 participants (SADI 24/29; BPD/DS 23/27). Observed mean %TWL was 34.3% after SADI and 36.7% after BPD/DS; the adjusted between-group difference in %TWL (SADI minus BPD/DS) was - 2.9% points (95% confidence interval [CI] - 8.7 to 2.9) with no statistically significant difference. 12 of 56 participants underwent at least one procedure-related reoperation (6/29 after SADI; 6/27 after BPD/DS). Internal herniation (n = 4) and malnutrition-related corrective surgery (n = 2) occurred only after BPD/DS. Vitamin D deficiency was more prevalent after BPD/DS than SADI (40.9% [9/22] vs. 12.5% [3/24]; p = 0.037), while a higher proportion of SADI patients had no deficiency in the combined panel of vitamin D, vitamin A, vitamin E, and zinc (44.4% [8/18] vs. 21.1% [4/19]). This composite difference was not statistically significant, and the small denominators and wide uncertainty preclude firm conclusions.
conclusionsThe trial did not provide evidence of a difference in 5-year weight loss; however, the wide confidence intervals preclude firm conclusions regarding comparative effectiveness. Overall reoperation frequency was similar, but BPD/DS was associated with a distinct pattern of reoperations, including internal herniation and malnutrition-related corrective surgery. Nutritional deficiencies were common after both procedures; vitamin D deficiency was more frequent after BPD/DS, and overall fat-soluble vitamin and trace element profiles appeared less favorable.
Indexed as
Identifiers
42270885What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.