Evidence map›Paper›PMID 42270635›Full record

ReviewNature communications2026

Navigating adoption barriers for microbial proteins in future food.

Rima Gnaim, Hakimi Kassim, Lisa Neidhardt, Thomas Gassler, Rodrigo Ledesma-Amaro

Abstract readReview
In one paragraph

Review in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rima Gnaim *Imperial College Centre for Engineering Biology, Imperial College London, London, UK.ORCID 0000-0002-9066-4761
Hakimi Kassim *Imperial College Centre for Engineering Biology, Imperial College London, London, UK.ORCID 0000-0002-9109-2099
Lisa Neidhardt *Imperial College Centre for Engineering Biology, Imperial College London, London, UK.ORCID 0000-0003-0256-5040
Thomas GasslerImperial College Centre for Engineering Biology, Imperial College London, London, UK.ORCID 0000-0003-1873-8807
Rodrigo Ledesma-AmaroImperial College Centre for Engineering Biology, Imperial College London, London, UK. r.ledesma-amaro@imperial.ac.uk.ORCID 0000-0003-2631-5898

Funding

European Commission (EC) (DEUSBIO - 949080),(PERFECOAT- 101022370) 101098826 (SKINDEV)RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/R01602X/1, BB/T013176/1, BB/T011408/1 - 19-ERACoBioTech- 33 SyCoLim, BB/X01911X/1, BB/Y008510/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) AI-4-EB BB/W013770/1, and EEBio Programme Grant EP/Y014073/1
6 · The paper itself

Abstract

Microbial biomass fermentation, in which microbes are cultivated to produce nutrient-dense biomass, offers a scalable route to sustainable protein production with low land, water, and greenhouse gas footprints. However, its shift from a speciality to a mainstream food continues to be difficult. Here, we move beyond technological overviews and propose a three-phase adoption framework: novelty barrier, early trust-building, and mainstream normalisation. This framework organises techno-economic, regulatory, and infrastructural barriers into a single trajectory. We trace single-cell proteins' rise, decline and resurgence, map engineering and policy enablers by phase, and outline levers to move microbial proteins into resilient food systems.

Indexed as

Bacterial ProteinsBiomassFermentationBacterial Proteins

Identifiers

PMID42270635
PMCPMC13269705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.